1439402-18-2Relevant academic research and scientific papers
Ambient Reductive Amination of Levulinic Acid to Pyrrolidones over Pt Nanocatalysts on Porous TiO2 Nanosheets
Xie, Chao,Song, Jinliang,Wu, Haoran,Hu, Yue,Liu, Huizhen,Zhang, Zhanrong,Zhang, Pei,Chen, Bingfeng,Han, Buxing
, p. 4002 - 4009 (2019)
Construction of N-substituted pyrrolidones from biomass-derived levulinic acid (LA) via reductive amination is a highly attractive route for biomass valorization. However, realizing this transformation using H2 as the hydrogen source under mild conditions is still very challenging. Herein, we designed porous TiO2 nanosheets-supported Pt nanoparticles (Pt/P-TiO2) as the heterogeneous catalyst. The prepared Pt/P-TiO2 was highly efficient for reductive amination of LA to produce various N-substituted pyrrolidones (34 examples) at ambient temperature and H2 pressure. Meanwhile, Pt/P-TiO2 showed good applicability for reductive amination of levulinic esters, 4-acetylbutyric acid, 2-acetylbenzoic acid, and 2-carboxybenzaldehyde. Systematic studies indicated that the strong acidity of P-TiO2 and the lower electron density of the Pt sites as well as the porous structure resulted in the excellent activity of Pt/P-TiO2.
Catalyst-free transformation of levulinic acid into pyrrolidinones with formic acid
Wei, Yawen,Wang, Chao,Jiang, Xue,Xue, Dong,Liu, Zhao-Tie,Xiao, Jianliang
supporting information, p. 1093 - 1096 (2014/03/21)
Levulinic acid (LA) is transformed into pyrrolidinones by formic acid in DMSO without a catalyst. Mechanistic studies suggest the involvement of an iminium intermediate and a rate-limiting hydride transfer step.
Highly efficient transformation of levulinic acid into pyrrolidinones by iridium catalysed transfer hydrogenation
Wei, Yawen,Wang, Chao,Jiang, Xue,Xue, Dong,Li, Jia,Xiao, Jianliang
supporting information, p. 5408 - 5410 (2013/07/05)
Levulinic acid (LA) is transformed into pyrrolidinones via iridium-catalysed reductive amination using formic acid as the hydrogen source under aqueous conditions. The catalytic system is the most active and performs under the mildest conditions ever reported for the reductive amination of LA.
