1439559-83-7 Usage
Molecular weight
530.06 g/mol
+ Chloro group (Cl)
A chlorine atom substituted into a carbon atom of the molecule.
+ Piperidinyl group (piperidin-4-yl)
A six-membered nitrogen-containing aromatic ring structure.
+ Phenoxy group (phenoxy)
A phenol molecule with one of its hydrogen atoms replaced by an ether group (-O-).
+ Pyrimidinyl group (pyrimidin-4-yl)
A six-membered nitrogen-containing ring structure.
+ Benzonitrile group (benzonitrile)
A benzene ring with a nitrile group (-C≡N) attached to it.
+ Pharmaceutical industry
May have potential as a drug candidate due to its unique structure and combination of functional groups.
+ Materials science and organic synthesis
May be used as a building block for the synthesis of other compounds.
+ Further research and development
Its complex structure and interesting properties make it a promising target for further study.
Check Digit Verification of cas no
The CAS Registry Mumber 1439559-83-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,9,5,5 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1439559-83:
(9*1)+(8*4)+(7*3)+(6*9)+(5*5)+(4*5)+(3*9)+(2*8)+(1*3)=207
207 % 10 = 7
So 1439559-83-7 is a valid CAS Registry Number.
1439559-83-7Relevant academic research and scientific papers
Discovery and optimization of tetramethylpiperidinyl benzamides as inhibitors of EZH2
Nasveschuk, Christopher G.,Gagnon, Alexandre,Garapaty-Rao, Shivani,Balasubramanian, Srividya,Campbell, Robert,Lee, Christina,Zhao, Feng,Bergeron, Louise,Cummings, Richard,Trojer, Patrick,Audia, James E.,Albrecht, Brian K.,Harmange, Jean-Christophe P.
, p. 378 - 383 (2014/05/06)
The identification and development of a novel series of small molecule Enhancer of Zeste Homologue 2 (EZH2) inhibitors is described. A concise and modular synthesis enabled the rapid development of structure-activity relationships, which led to the identification of 44 as a potent, SAM-competitive inhibitor of EZH2 that dose-dependently decreased global H3K27me3 in KARPAS-422 lymphoma cells.
MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
-
, (2013/06/06)
Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
