14397-64-9Relevant articles and documents
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents
Gangjee, Aleem,Zhao, Ying,Ihnat, Michael A.,Thorpe, Jessica E.,Bailey-Downs, Lora C.,Kisliuk, Roy L.
experimental part, p. 4217 - 4225 (2012/09/08)
We designed, synthesized and evaluated 13 novel tricyclic indeno[2,1-d]pyrimidines as RTK inhibitors. These analogues were synthesized via a Dieckmann condensation of 1,2-phenylenediacetonitrile followed by cyclocondensation with guanidine carbonate to af
Benzobicycloalkane ketones
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, (2008/06/13)
Benzobicycloalkane amines, their pharmacologically acceptable addition salts, intermediates therefore the processes for their preparation and use. The compounds of the invention exert analgesic and anti-inflammatory activity.