143982-35-8Relevant articles and documents
Diversity-Oriented Synthesis of β-Lactams and γ-Lactams by Post-Ugi Nucleophilic Cyclization: Lewis Acids as Regioselective Switch
Li, Zhenghua,Sharma, Upendra Kumar,Liu, Zhen,Sharma, Nandini,Harvey, Jeremy N.,Van Der Eycken, Erik V.
supporting information, p. 3957 - 3962 (2015/06/30)
Heterocyclic fused α-methylene β-lactams were successfully synthesized by a post-Ugi InIII-catalyzed intramolecular addition reaction. Switching from InCl3 to AlCl3 led to the regioselective synthesis of α,β-unsaturated γ-lactams. Moreover, replacing terminal alkynes by substituted alkynes in the Ugi adducts resulted in the exclusive formation of γ-lactams with both catalytic systems. A regioselective approach for the synthesis of heterocyclic fused α-methylene β-lactams and α,β-unsaturated γ-lactams by employing a Ugi reaction followed by InIII- or AlIII-catalyzed intramolecular nucleophilic addition is reported.
Pyrrolization processes of vinyl substituted imidazo[1,2-a]pyridine, pyrimidine and 1,8-naphthyridine
Chavignon,Teulade,Madesclaire,Gueiffier,Blache,Viols,Chapat,Dauphin
, p. 691 - 697 (2007/10/02)
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