14400-73-8

Usage

Uses

Used in Pharmaceutical Industry:
(2R,7S)-octa-3,5-diyne-2,7-diol is used as a synthetic building block for the production of pharmaceuticals. Its unique structure containing triple bonds and hydroxyl groups makes it useful in the synthesis of various drug molecules.
Used in Agrochemical Industry:
(2R,7S)-octa-3,5-diyne-2,7-diol is used as a synthetic building block for the production of agrochemicals. Its unique structure allows for the creation of new agrochemical compounds with improved properties.
Used in Materials Industry:
(2R,7S)-octa-3,5-diyne-2,7-diol is used as a synthetic building block for the development of new materials. Its unique structure containing triple bonds and hydroxyl groups makes it useful in the production of advanced materials with specific properties.
Used in Optoelectronics:
(2R,7S)-octa-3,5-diyne-2,7-diol is used in the field of optoelectronics due to its conjugated and reactive nature. Its unique structure allows for the development of new optoelectronic devices with improved performance.
Used in Nanotechnology:
(2R,7S)-octa-3,5-diyne-2,7-diol has potential applications in nanotechnology due to its conjugated and reactive nature. Its unique structure makes it a promising candidate for the development of new nanomaterials and nanodevices.

Upstream product

• 2028-63-9 but-3-yn-2-ol 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 
• 75-07-0 acetaldehyde 
• 2060-24-4 4-bromo-3-butyn-2-ol 
• 1262958-22-4 2-iodo-3,5,6-trimethoxytoluene 

Downstream Products

• 19686-96-5 octane-2,7-diol 
• 64330-66-1 1,6-dioxo-2,4-diene 

Relevant academic research and scientific papers

Synthesis of conjugated diallenes by double [2,3]-sigmatropic rearrangement of conjugated diyne trichloromethanesulfenates

The preparation of several 2,4-diyne-1,6-diols and their esterification with trichloromethanesulfenyl chloride is described. The thus generated bis- propargylic trichloromethanesulfenates undergo spontaneous double [2,3]- sigmatropic rearrangement which leads to the formation of conjugated diallenic trichloromethyl sulfoxides in good to excellent yields.

Synthesis of 21,23-selenium- and tellurium-substituted 5-porphomethenes, 5,10-porphodimethenes, 5,15-porphodimethenes, and porphotrimethenes and their interactions with mercury

The 3+1 condensation of symmetrical 16-Selena/telluratripyrranes with symmetrical selenophene-2,5-diols/tellurophene-2,5-diols in the presence of BF3-etheratre or BF3-methanol followed by oxidation with DDQ gave 5,10-porphodimethenes, whereas the process with unsymmetrical selenophene-2,5-diols/tellurophene-2,5-diols gave 5-porphomethenes. In addition, the reaction of unsymmetrical 16-Selena/telluratripyrranes with symmetrical selenophene-2,5-diols/tellurophene-2,5-diols gave the corresponding porphotrimethenes, whereas the process with unsymmetrical selenophene-2,5-diols/tellurophene-2,5-diols gave the 5,15-porphodimethenes. The structures of different products were characterized by IR, 1H and 13C NMR, 1H-1H COSY, CHN analysis, and mass spectrometry. The binding of mercury with the calix[4]phyrins mentioned above had been observed in the decreasing order of porphodimethenes > porphomethenes > porphotrimethenes by UV-vis and 1H NMR spectroscopy.

Synthesis of 5,10,15,20-meso-unsubstituted and 5,10,15,20-meso-substituted- 21,23-ditellura/diselena core-modified porphyrinogens: Oxidation and detection of mercury(ii)

Tellurium and selenium incorporated 5,10,15,20-meso-unsubstituted-21,23- ditellura/diselena core-modified porphyrinogens (N2Te2 and N2Se2), 5,10,15,20-meso-unsubstituted-21-tellura/selena core-modified porphyrinogens (N3Te and N3Se) and fully substituted meso-carbons porphyrinogens (N2Te2, N 2Se2 and higher analogs) are synthesized by 3 + 1 condensation of tellurophene/selenophene dipyrranes and their corresponding diols in the presence of BF3-etharate or BF3-methanol. The meso-unsubstituted and substituted porphyrinogens were oxidized with chloranil/0.1% aqueous FeCl3 in CHCl3 at room temperature to obtain the corresponding porphines and porphyrins which are further reduced to corresponding chlorin and bacteriochlorin, whereas the fully meso-substituted porphyrinogens were found to be good ligands for Hg2+. The structures of the products were characterized by IR, 1H, 13C, 125Te, 77Se NMR, CHN analysis, mass spectrometry and single-crystal XRD.

Ethynylbenzenoid metabolites of Antrodia camphorata: Synthesis and inhibition of TNF expression

An improved synthesis of the anti-inflammatory natural product antrocamphin A (2), involving a key Castro-Stephens reaction, is presented, along with the first total synthesis of its congener antrocamphin B (3). Approaches towards the more complex co-meta

Selectivity in the Ruthenium-catalyzed Alder ene reactions of di- and triynes

Ruthenium-catalyzed Alder ene reactions between diynes and triynes with terminal alkenes gave the corresponding enynes and enediynes with high regio- and site-selectivity. The selectivity profile clearly indicates that one of the alkynyl moieties of 1,3-diynes not participating in the reaction determines the regiochemistry, whereas the interplay between steric hindrance and polar substituents at the propargylic sites determines the site-selectivity. Copyright