144060-68-4

Upstream product

• 20582-55-2 ethyl 4-methylthiazole-5-carboxylate 
• 383869-57-6 4-bromo-2-nitro-1-(propan-2-yloxy)benzene 
• 7693-52-9 4-bromo-2-nitrophenol 

Downstream Products

• 144060-84-4 ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methyl-5-thiazolecarboxylate 

Relevant academic research and scientific papers

XANTHINE OXIDASE INHIBITOR

Provided are a xanthine oxidase inhibitor, a drug for improving vascular endothelial function, and an excellent therapeutic or prophylactic drug for diseases associated with xanthine oxidase such as gout, hyperuricaemia, and for diseases associated with vascular endothelial functional disorder containing a compound represented in a formula (I) or the pharmaceutically acceptable salt thereof as an active ingredient.

AZOLE BENZENE DERIVATIVE

The present invention provides: a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, which has an excellent inhibitory activity on xanthine oxidase and is useful as a therapeutic agent or a prophylactic agent for diseases associated with xanthine oxidase, such as gout, hyperuricemia, tumor lysis syndrome, urinary tract stone, hypertension, dyslipidemia, diabetes, cardiovascular diseases including arteriosclerosis and heart failure, renal diseases including diabetic nephropathy, respiratory diseases including chronic obstructive pulmonary disease, inflammatory bowel disease or autoimmune diseases; and a medicine or a pharmaceutical composition comprising the compound or the salt as an active ingredient.