1441181-09-4

Basic information

• Product Name: 3-iodo-4-phenyl-2H-1-benzopyran-2-one
• Synonyms: 3-iodo-4-phenyl-2H-1-benzopyran-2-one
• CAS NO: 1441181-09-4
• Molecular Weight: 348.14
• Mol File: 1441181-09-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-iodo-4-phenyl-2H-1-benzopyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-iodo-4-phenyl-2H-1-benzopyran-2-one(1441181-09-4)
• EPA Substance Registry System: 3-iodo-4-phenyl-2H-1-benzopyran-2-one(1441181-09-4)

Safety Data

• Hazardous Substances Data: 1441181-09-4(Hazardous Substances Data)

Upstream product

• 637-44-5 phenylpropyolic acid 
• 100954-03-8 phenyl 3-phenylprop-2-ynoate 
• 853304-33-3 3-iodo-4-phenyl-2H-benzopyran 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 1441180-38-6 3-ethoxy-1-(2-methoxyphenyl)-1-phenylpropyl-2-yn-1-ol 
• 71103-99-6 2-Benzoyl-1-<(methoxymethyl)oxy>benzene 
• 2553-04-0 ortho-methoxybenzophenone 
• 1441180-50-2 3-ethoxy-1-(2-(methoxymethoxy)phenyl)-1-phenylprop-2-yn-1-ol 

Relevant articles and documents

Sunlight-promoted cyclization: Versus decarboxylation in the reaction of alkynoates with N -iodosuccinimide: Easy access to 3-iodocoumarins

A sunlight-initiated radical conversion of aryl alkynoates to 3-iodocoumarins has been achieved using N-iodosuccinimide as the iodine source without the use of a catalyst or additive. Experimental, X-ray analysis, and computational studies indicate that the reaction under sunlight proceeds through iodination, spirocyclization and ring expansion to form the kinetic product. The sunlight-driven reaction provides a green pathway to especially valuable 3-halocoumarins derivatives.

Photoinduced cyclization of alkynoates to coumarins with N-Iodosuccinimide as a free-radical initiator under ambient and metal-free conditions

An efficient photoinduced strategy for the preparation of coumarins was developed. In the presence of N-iodosuccinimide (NIS) as a free-radical initiator and under LED (380–385 nm) irradiation and metal-free conditions, the reaction of alkynoates underwen

Hypervalent iodine compound containing heterocyclic ring as well as preparation method and application thereof

The invention discloses a hypervalent iodine compound containing a heterocyclic ring as well as a preparation method and application thereof. A structure of the compound is shown as a formula (I): theformula (I) is shown in the description, wherein R is selected from hydrogen, halogen, alkyl, alkoxy, halogenated alkyl, halogenated alkoxy, nitryl, cyano, hydroxyl or -COOR'; R' is alkyl or halogenated alkyl; and Het is substituted or non-substituted 1,4-benzopyranone, substituted or non-substituted quinolone, substituted or non-substituted isoquinoline, substituted or non-substituted thiobenzopyranone, substituted or non-substituted coumarin and substituted or non-substituted oxepin. The compound disclosed by the invention is novel in structure and is the hypervalent iodine compound containing the heterocyclic ring; the hypervalent iodine compound is stable in structure and simple in preparation method; and meanwhile, the hypervalent iodine compound has a very good inhibition effect onML-1 and MOLM-13 cells and has an extremely great application prospect on prevention and/or treatment effect on leukemia.