144205-47-0Relevant articles and documents
Design, synthesis, acaricidal activity, and mechanism of oxazoline derivatives containing an oxime ether moiety
Li, Yongqiang,Li, Chaojie,Zheng, Yanlong,Wei, Xingcun,Ma, Qiaoqiao,Wei, Peng,Liu, Yuxiu,Qin, Yaoguo,Yang, Na,Sun, Yufeng,Ling, Yun,Yang, Xinling,Wang, Qingmin
, p. 3064 - 3072 (2014)
Two series of novel 2,4-diphenyl-1,3-oxazolines containing an oxime ether moiety were designed and synthesized via the key intermediate N-(2-chloro-1-(p-tolyl)ethyl)-2,6-difluorobenzamide. The bioassay results showed that the target compounds with an oxime ether substituent at the para position of 4-phenyl exhibited excellent acaricidal activity against Tetranychus cinnabarinus in the laboratory. Moreover, all of the target compounds had much higher activities than etoxazole, as the ovicidal and larvicidal activities of the target compounds I-a-I-l and II-a-II-n against T. cinnabarinus were all over 90% at 0.001 mg L-1, but etoxazole gave only 30% and 40% respectively at the same concentration. The activity order of compounds with regard to acaricidal activity in vivo was almost consistent with their affinity activity with sulfonylurea receptor (SUR) of Blattella germanica in vitro, hence, it was supposed that the acaricidal mechanism of action of the target compounds was that they can bind with the site of SUR and therefore inhibit chitin synthesis. Moreover, the eminent effect of the compound II-l, [2-(trifluoromethyl)benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol- 4-yl)benzyl) oxime], against Panonychus citri and T. cinnabarinus in the field indicated that II-l exhibited a promising application prospect as a new candicate for controlling spider mites in the field.
Synthesis of Air- and Moisture-Stable, Storable Chiral Oxorhenium Complexes and Their Application as Catalysts for the Enantioselective Imine Reduction
Das, Braja Gopal,Nallagonda, Rajender,Dey, Dhananjay,Ghorai, Prasanta
supporting information, p. 12601 - 12605 (2015/09/01)
Air-/moisture-stable, crystalline, and storable chiral salicyloxazoline based oxorhenium(V) complexes have been synthesized and their catalytic application for the asymmetric reduction of ketimines using hydrosilane as hydride source is disclosed. A broad substrate scope, high yields, and excellent enantioselectivities (up to 99 %) are attained. Furthermore, the syntheses of enantiopure α-amino esters, γ- and δ-lactams, and isoindolinones have also been carried out using this methodology. Finally, the method has been applied to synthetic targets of pharmaceutical relevance, such as R-(+)-salsolidine and R-(+)-crispine A.
Design, synthesis, acaricidal activity, and mechanism of oxazoline derivatives containing an oxime ether moiety
Li, Yongqiang,Li, Chaojie,Zheng, Yanlong,Wei, Xingcun,Ma, Qiaoqiao,Wei, Peng,Liu, Yuxiu,Qin, Yaoguo,Yang, Na,Sun, Yufeng,Ling, Yun,Yang, Xinling,Wang, Qingmin
, p. 3064 - 3072 (2015/04/22)
Two series of novel 2,4-diphenyl-1,3-oxazolines containing an oxime ether moiety were designed and synthesized via the key intermediate N-(2-chloro-1-(p-tolyl)ethyl)-2,6-difluorobenzamide. The bioassay results showed that the target compounds with an oxime ether substituent at the para position of 4-phenyl exhibited excellent acaricidal activity against Tetranychus cinnabarinus in the laboratory. Moreover, all of the target compounds had much higher activities than etoxazole, as the ovicidal and larvicidal activities of the target compounds I-a-I-l and II-a-II-n against T. cinnabarinus were all over 90% at 0.001 mg L-1, but etoxazole gave only 30% and 40% respectively at the same concentration. The activity order of compounds with regard to acaricidal activity in vivo was almost consistent with their affinity activity with sulfonylurea receptor (SUR) of Blattella germanica in vitro, hence, it was supposed that the acaricidal mechanism of action of the target compounds was that they can bind with the site of SUR and therefore inhibit chitin synthesis. Moreover, the eminent effect of the compound II-l, [2-(trifluoromethyl)benzaldehyde O-(4-(2-(2,6-difluorophenyl)-4,5-dihydrooxazol-4-yl)benzyl) oxime], against Panonychus citri and T. cinnabarinus in the field indicated that II-l exhibited a promising application prospect as a new candicate for controlling spider mites in the field.
Mono et dinitrosation en position benzylique des complexes du benzene chrometricarbonyle. Synthese directe d'oximes et d'hydroximates
Senechal-Tocquer, M.-C.,Senechal, D.,Bihan, J.-Y. Le,Gentric, D.,Caro, B.,et al.
, p. 261 - 278 (2007/10/02)
In basic media, aromatic hydrocarbons and benzylmethylethers complexed by Cr(CO)3 units are readily nitrosated at the benzylic position by tBuONO, giving rise to Z and E oximes and hydroximates in moderate to excellent yields.With the meta-xylene and isochromane complexes it is possible to obtain a dinitrosation.
