144294-89-3Relevant academic research and scientific papers
SYNTHESIS OF 2-ARYL-3-HYDROXYQUINOLIN-4(1H)-ONES
Hradil, Pavel,Jirman, Josef
, p. 1357 - 1366 (1995)
Eight substituted phenacyl anthranilates have been prepared by reaction of sodium anthranilate with substituted phenacyl halides in dimethylformamide in the yields from 31 to 93percent.The phenacyl esters were cyclized in polyphosphoric acid or by mere heating to give the respective substituted 2-aryl-3-hydroxyquinolin-4(1H)-ones in the yields from 77 to 98percent.All the compounds prepared have been characterized by their 1H and 13C NMR spectra.
