1443022-06-7

Basic information

• Product Name: 4-(4-(5-(4-chlorophenyl)-2-(4-methoxyphenyl)-1H-pyrrol-3-yl)-3-p-tolyl-1H-pyrazol-1-yl)benzenesulfonamide
• Synonyms: 4-(4-(5-(4-chlorophenyl)-2-(4-methoxyphenyl)-1H-pyrrol-3-yl)-3-p-tolyl-1H-pyrazol-1-yl)benzenesulfonamide
• CAS NO: 1443022-06-7
• Molecular Weight: 595.121
• Mol File: 1443022-06-7.mol

Chemical Properties

• CAS DataBase Reference: 4-(4-(5-(4-chlorophenyl)-2-(4-methoxyphenyl)-1H-pyrrol-3-yl)-3-p-tolyl-1H-pyrazol-1-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-(5-(4-chlorophenyl)-2-(4-methoxyphenyl)-1H-pyrrol-3-yl)-3-p-tolyl-1H-pyrazol-1-yl)benzenesulfonamide(1443022-06-7)
• EPA Substance Registry System: 4-(4-(5-(4-chlorophenyl)-2-(4-methoxyphenyl)-1H-pyrrol-3-yl)-3-p-tolyl-1H-pyrazol-1-yl)benzenesulfonamide(1443022-06-7)

Safety Data

• Hazardous Substances Data: 1443022-06-7(Hazardous Substances Data)

Upstream product

• 17852-52-7 4-hydrazinobenzene-1-sulfonamide hydrochloride 
• 1061214-06-9 4-[2-[1-(4-methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide 
• 1135952-94-1 C₂₀H₂₀N₄O₃S 
• 1135953-00-2 4-(4-formyl-3-(p-tolyl)-1Hpyrazol-1-yl)benzenesulfonamide 
• 1443021-98-4 4-(4-(4-(4-chlorophenyl)-1-(4-methoxyphenyl)-1,4-dioxobutan-2-yl)-3-p-tolyl-1H-pyrazol-1-yl)benzenesulfonamide 
• 122-00-9 para-methylacetophenone 

Relevant articles and documents

Synthesis of novel 1,3,4-trisubstituted pyrazoles as anti-inflammatory and analgesic agents

Some novel 1,3,4-trisubstituted pyrazoles were synthesized and screened for their anti-inflammatory and analgesic activities as well as their ulcerogenic liability. They showed anti-inflammatory and analgesic activities with better GIT tolerance than the standard drug phenylbutazone. In addition, IC 50 values for 5e and 8e were recorded. Compound 5e was found to be the most active one as anti-inflammatory and analgesic agent. On the other hand, COX-1/COX-2 isozyme selectivity was also done which showed equal inhibition to both isoforms.