1443035-31-1

Basic information

• Product Name: C₉H₈BrFNO₂^(1-)*Na⁽¹⁺⁾
• Synonyms: C₉H₈BrFNO₂^(1-)*Na⁽¹⁺⁾
• CAS NO: 1443035-31-1
• Molecular Weight: 284.06
• Mol File: 1443035-31-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₉H₈BrFNO₂^(1-)*Na⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: C₉H₈BrFNO₂^(1-)*Na⁽¹⁺⁾(1443035-31-1)
• EPA Substance Registry System: C₉H₈BrFNO₂^(1-)*Na⁽¹⁺⁾(1443035-31-1)

Safety Data

• Hazardous Substances Data: 1443035-31-1(Hazardous Substances Data)

Upstream product

• 1213855-88-9 (R)-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionic acid methyl ester 
• 1266784-23-9 (RS)-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionic acid 
• 1350523-51-1 rac-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionitrile 
• 198477-89-3 1-(5-bromo-2-fluorophenyl)ethan-1-one 

Downstream Products

• 1443035-33-3 C₁₁H₉BrClFNO₃^(1-)*Na⁽¹⁺⁾ 
• 1443035-35-5 (3R)-3-(5-bromo-2-fluorophenyl)-3-methylmorpholine-2,5-dione 
• 1443035-37-7 C₁₂H₁₀BrF₄NO₃ 
• 1443035-39-9 (5R)-5-(5-bromo-2-fluorophenyl)-6-chloro-5-methyl-6-(trifluoromethyl)morpholin-3-one 
• 1443035-41-3 (5R)-5-(5-bromo-2-fluorophenyl)-6-(difluoromethylene)-5-methylmorpholin-3-one 
• 1443035-43-5 (5R)-5-(5-bromo-2-fluorophenyl)-6-(difluoromethylene)-5-methylmorpholin-3-thione 
• 1443259-48-0 (5R)-5-(5-bromo-2-fluorophenyl)-5-methyl-6-(trifluoromethyl)-morpholin-3-one 
• 1352419-89-6 (5R)-5-(5-bromo-2-fluoro-phenyl)-5-methyl-6-(trifluoromethyl)-morpholine-3-thione 
• 1443259-50-4 (5R,6S)-5-(5-bromo-2-fluorophenyl)-5-methyl-6-(trifluoromethyl)-2,6-dihydro-1,4-oxazin-3-amine 
• 1443259-26-4 (5R,6R)-5-{2-fluoro-5-[(3-methoxypyridin-2-yl)amino]phenyl}-5-methyl-6-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-3-amine 
• 1443259-27-5 (5R,6R)-5-[2-fluoro-5-(pyrimidin-2-ylamino)phenyl]-5-methyl-6-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-3-amine 
• 1443259-31-1 2-((3-((2R,3R)-5-amino-3-methyl-2-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl)-4-fluorophenyl)amino)nicotinonitrile 
• 1443035-45-7 (5R)-5-(5-bromo-2-fluorophenyl)-6-(difluoromethylene)-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine 
• 1443035-47-9 (5R)-5-(5-amino-2-fluorophenyl)-6-(difluoromethylene)-5-methyl-5,6-dihydro-2H-1,4-oxazin-3-amine 

Relevant articles and documents

5-(3-AMINOPHENYL)-5-ALKYL-5,6-DIHYDRO-2H-[1,4]OXAZIN-3-AMINE DERIVATIVES

The present invention relates to novel 5-(3-aminophenyl)-5-alkyl-5,6-dihydro-2H-[1,4]oxazin-3-amine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also direct

6-DIFLUOROMETHYL-5,6-DIHYDRO-2H-[1,4]OXAZIN-3-AMINE DERIVATIVES

The invention relates to novel 6-difluoromethyl-5,6-dihydro-2H-[l,4]oxazin-3- amine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also directed to pharmaceut