144320-50-3

Upstream product

• 170508-53-9 Methyl 3-<2,5-bis<(2-methoxyethoxy)methoxy>phenyl>propanoate 
• 170508-52-8 Methyl (2E)-3-<2,5-bis<(2-methoxyethoxy)methoxy>phenyl>acrylate 
• 170508-54-0 3-<2,5-Bis<(2-methoxyethoxy)methoxy>phenyl>-1-propanol 
• 170508-51-7 2,5-Bis<(2-methoxyethoxy)methoxy>benzaldehyde 
• 1194-98-5 2,5-Dihydroxybenzaldehyde 
• 5927-18-4 trimethyl phosphonoacetate 

Downstream Products

• 144320-51-4 3-[(5Z,10Z,14Z,19Z)-(7S,8R)-8-[3-(2,5-Dihydroxy-phenyl)-propoxy]-18-(2-methoxycarbonyl-ethyl)-7-methoxycarbonylmethyl-3,7,12,17-tetramethyl-7,8,21,23-tetrahydro-porphin-2-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of Oxochlorins from the Red Blood Pigment Heme and Their Transformation into Potentially Biologically Active Chlorin Derivatives

The hydrochlorin rac-3 was prepared from the readily accessible chlorins rac-5a, b.The alcohol function of rac-3 could be used to attach an estrogen residue 28 and the hydroquinone 19 to yield the chlorin estrogen ethers 32a, b and the chlorin hydroquinone ether rac-30 respectively.The prepared chlorin estrogen derivatives might be useful as sensitizers and fluorescence markers for photodynamic therapy and other diagnostic/therapeutic applications.The chlorin hydroquinone ether is of interest as a potential artificial photosynthesis system, which contains a "natural" chlorin as a structural subunit in contrast to previously synthesized model systems based on porphyrins. - Keywords: Porphyrins / Chlorins / Estradiols / Quinones / Tumor therapy, photodynamic