1443233-47-3Relevant academic research and scientific papers
Transition metal-free iodine-promoted haloamination of unfunctionalized olefins
Li, Wei,Liu, Gong-Qing,Cui, Bin,Zhang, Li,Li, Ting-Ting,Li, Lin,Duan, Lili,Li, Yue-Ming
, p. 13509 - 13513 (2014/04/03)
A transition metal-free route to 3-halopiperidines and 2- halomethylpiperidines was described. In the presence of iodine, potassium persulfate and a suitable halogen source, intramolecular haloamination of 4-penten-1-amines and 5-hexen-1-amines proceeded readily, leading to the corresponding substituted piperidines in good isolated yields. This journal is the Partner Organisations 2014.
One-pot preparation of 3-chloropiperidine compounds via Cu(II)-promoted intramolecular chloroamination of unfunctionalized olefins
Li, Run-Lin,Liu, Gong-Qing,Li, Wei,Wang, Yu-Mei,Li, Lin,Duan, Lili,Li, Yue-Ming
, p. 5867 - 5873 (2013/07/27)
3-Chloropiperidine compounds were obtained via Cu(II)-promoted one-pot intramolecular chloroamination of N-benzyl-4-penten-1-amines and subsequent rearrangement. The reaction conditions leading to this skeleton were studied, and the structure of the product was confirmed by NMR as well as X-ray diffraction experiments.
A new method for intramolecular chloroamination of unfunctionalized olefins
Liu, Gong-Qing,Li, Wei,Li, Yue-Ming
supporting information, p. 395 - 402 (2013/05/08)
A new method for the intramolecular chloroamination of unfunctionalized olefins is reported. The reactions were carried out at room temperature for 3 h using hydrated copper(II) chloride as both promoter and chlorine source, and the corresponding vincinal haloamines were obtained in good isolated yields.
