53001-06-2

Basic information

• Product Name: Benzeneethanamine, b-phenyl-b-2-propenyl-
• CAS NO: 53001-06-2
• Molecular Formula: C17H19N
• Molecular Weight: 237.345
• Mol File: 53001-06-2.mol
• Article Data: 38

Chemical Properties

• CAS DataBase Reference: Benzeneethanamine, b-phenyl-b-2-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanamine, b-phenyl-b-2-propenyl-(53001-06-2)
• EPA Substance Registry System: Benzeneethanamine, b-phenyl-b-2-propenyl-(53001-06-2)

Safety Data

• Hazardous Substances Data: 53001-06-2(Hazardous Substances Data)

Upstream product

• 108-90-7 chlorobenzene 
• 126899-77-2 1,1-diphenyl-3-butene-1-carboxaldehyde 
• 55103-28-1 1-tert.-Butylamino-2,2-diphenylethylen 
• 947-91-1 Diphenylacetaldehyde 
• 86-29-3 Diphenylacetonitrile 
• 5558-71-4 2,2-diphenyl-pent-4-enenitrile 

Downstream Products

• 1009105-66-1 N-(cyclohexylmethyl)-2,2-diphenylpent-4-en-1-amine 
• 50259-75-1 2-methyl-4,4-diphenylpyrrolidine 
• 1214263-63-4 C₁₇H₁₇N 
• 1214263-67-8 C₁₇H₁₆⁽²⁾HN 
• 1214263-68-9 C₁₇H₁₆⁽²⁾HN 
• 1214263-66-7 2-methyl-4,4-diphenylpyrrolidine 
• 1245741-89-2 C₁₉H₁₈F₃NO 
• 1393480-62-0 N-(2,2-diphenylpent-4-en-1-yl)benzenesulfonamide 
• 1411774-94-1 N-(2,2-diphenylpent-4-en-1-yl)-4-methoxybenzene-1-sulfonamide 

Relevant articles and documents

Asymmetric "clip-Cycle" Synthesis of Pyrrolidines and Spiropyrrolidines

The development of an asymmetric "clip-cycle"synthesis of 2,2- and 3,3-disubstituted pyrrolidines and spiropyrrolidines, which are increasingly important scaffolds in drug discovery programs, is reported. Cbz-protected bis-homoallylic amines were activate

Palladium(II)-Catalyzed Aminotrifluoromethoxylation of Alkenes: Mechanistic Insight into the Effect of N-Protecting Groups

An efficient palladium-catalyzed regioselective 5-exo aminotrifluoromethoxylation of alkenes has been established herein, which provides a practical route towards the synthesis of OCF3-containing pyrrolidines. tert-Butyloxycarbonyl (Boc) as an amino protecting group plays a significant role in both the chemo- and regioselectivities. In addition, preliminary mechanistic studies reveal that the amino protecting group of substrates and the counter anion of palladium catalyst play critical roles in reaction efficiency presumably due to an isomerization of alkyl- Pd(II) intermediates. Moreover, the asymmetric 5-exo aminotrifluoromethoxylation reaction has also been achieved by introducing a sterically bulky pyridinyl-oxazoline ligand.

Aerobic intramolecular aminothiocyanation of unactivated alkenes promoted by in situ generated iodine thiocyanate

Aerobic intramolecular aminothiocyanation of unactivated alkenes has been developed by in situ generated iodine thiocyanate under open-flask conditions. This protocol provides a concise and efficient method for synthesizing SCN-containing pyrrolidine, piperidine and indoline derivatives with isolated yields of up to 87%. Furthermore, mixing iodine and sodium thiocyanate with oxygen afforded iodine thiocyanate (ISCN) and dithiocyanatoiodate [I(SCN)2]- which were testified by liquid chromatography mass spectrometry. A mechanistic investigation indicates that iodonium ion and sulfonium ion intermediates might be involved in this transformation.