1444018-17-0

Basic information

• Product Name: 2-(5-fluoro-2-nitrophenyl)naphthalene
• Synonyms: 2-(5-fluoro-2-nitrophenyl)naphthalene
• CAS NO: 1444018-17-0
• Molecular Weight: 267.259
• Mol File: 1444018-17-0.mol

Chemical Properties

• CAS DataBase Reference: 2-(5-fluoro-2-nitrophenyl)naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-fluoro-2-nitrophenyl)naphthalene(1444018-17-0)
• EPA Substance Registry System: 2-(5-fluoro-2-nitrophenyl)naphthalene(1444018-17-0)

Safety Data

• Hazardous Substances Data: 1444018-17-0(Hazardous Substances Data)

Upstream product

• 320-98-9 5-fluoro-2-nitrobenzoic acid 
• 2106-50-5 2-chloro-4-fluoro-1-nitrobenzene 
• 32316-92-0 naphthalene-2-boronic acid 
• 135-19-3 β-naphthol 
• 92449-40-6 potassium 5-fluoro-2-nitrobenzoate 
• 10290-91-2 naphthalen-2-yl methanesulfonate 

Relevant articles and documents

NaI/PPh3-Mediated Photochemical Reduction and Amination of Nitroarenes

A mild transition-metal- and photosensitizer-free photoredox system based on the combination of NaI and PPh3 was found to enable highly selective reduction of nitroarenes. This protocol tolerates a broad range of reducible functional groups such as halogen (Cl, Br, and even I), aldehyde, ketone, carboxyl, and cyano. Moreover, the photoredox catalysis with NaI and stoichiometric PPh3 provides also an alternative entry to Cadogan-type reductive amination when o-nitrobiarenes were used.

Visible-light-driven Cadogan reaction

Visible-light-driven photochemical Cadogan-type cyclization has been discovered. The organic D-A type photosensitizer 4CzIPN found to be an efficient mediator to transfer energy from photons to the transient intermediate that breaks the barriers of deoxygenation in Cadogan reaction and enables a mild metal-free access to carbazoles and related heterocycles. DFT calculation results indicate mildly endergonic formation of the intermediate complex of nitrobiarenes and PPh3, which corresponds with experimental findings regarding reaction temperature. The robust synthetic capacity of the photoredox Cadogan reaction systems has been demonstrated by the viable productivity of a broad range of carbazoles and related N-heterocycles with good tolerance of various functionalities.

Method for preparing biaryl hydrocarbon compound by Suzuki coupling reaction

The invention discloses a preparation method of a biaryl hydrocarbon compound as shown in a structural formula III (the structural formula and substituent are shown in the specification), which comprises the following steps: adding a nonionic surfactant into a reaction system, and carrying out Suzuki coupling reaction on chlorinated aromatic hydrocarbon as shown in a structural formula I and arylboronic acid as shown in a structural formula II. The preparation method provided by the invention is high in chlorinated aromatic hydrocarbon reaction activity, low in raw material cost, mild in reaction condition, green and environment-friendly.

Decarboxylative cross-coupling of mesylates catalyzed by copper/palladium systems with customized imidazolyl phosphine ligands

The activation of the inert C-O bonds in mesylates through the use of a new class of imidazolyl phosphines allows the decarboxylative coupling of aryl mesylates as well as polysubstituted alkenyl mesylates. Variation of the ligands leads to two complementary methods providing the corresponding biaryls and polysubstituted olefins in good yields. Copyright