14442-24-1Relevant academic research and scientific papers
Development of a safely handleable synthetic equivalent of cyanonitrile oxide by 1,3-dipolar cycloaddition of nitroacetonitrile
Nishiwaki, Nagatoshi,Kumegawa, Yuta,Iwai, Kento,Yokoyama, Soichi
supporting information, p. 7903 - 7905 (2019/07/10)
Dianionic cyano-aci-nitroacetate affords 3-cyanoisoxazol(in)es upon heating with a range of dipolarophiles in the presence of hydrochloric acid. In this reaction, nitroacetonitrile is formed as an intermediate active species, which serves as a synthetic e
Structural Investigation of 3,5-Disubstituted Isoxazoles by 1H-Nuclear Magnetic Resonance
Sechi, Mario,Sannia, Luciano,Orecchioni, Maria,Carta, Fabrizio,Paglietti, Giuseppe,Neamati, Nouri
, p. 1097 - 1102 (2007/10/03)
HIV-1 integrase (IN) is a very promising and validated target for the development of therapeutic agents against AIDS. In an effort to design and synthesize biological isosteric analogs of β-diketoacid-containing inhibitors of IN, we prepared a series of s
Novel reaction of [bis(acyloxy)iodo]arenes
Sheremetev, Aleksei B.,Konkina, Svetlana M.
, p. 277 - 278 (2007/10/03)
The reaction of [(diacetoxy)iodo]benzene with furazan dicarboxylic acid was accompanied by a novel decarboxylative ring-cleavage reaction; the cyanogen N-oxide, reactive intermediate generated in the process, was dimerised or trapped by a dipolarophile.
