14442-48-9

Basic information

• Product Name: ethyl (Z)-2-cyano-3-phenyl-pent-2-enoate
• Synonyms: ethyl (Z)-2-cyano-3-phenyl-pent-2-enoate
• CAS NO: 14442-48-9
• Molecular Formula: C₁₄H₁₅NO₂
• Molecular Weight: 229.27
• Mol File: 14442-48-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 342.1°Cat760mmHg
• Flash Point: 162.4°C
• Appearance: /
• Density: 1.076g/cm³
• Vapor Pressure: 7.7E-05mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: ethyl (Z)-2-cyano-3-phenyl-pent-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (Z)-2-cyano-3-phenyl-pent-2-enoate(14442-48-9)
• EPA Substance Registry System: ethyl (Z)-2-cyano-3-phenyl-pent-2-enoate(14442-48-9)

Safety Data

• Hazardous Substances Data: 14442-48-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 29, p. 520, 1986 DOI: 10.1021/jm00154a016

InChI:InChI=1/C14H15NO2/c1-3-12(11-8-6-5-7-9-11)13(10-15)14(16)17-4-2/h5-9H,3-4H2,1-2H3/b13-12-

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 93-55-0 1-phenyl-propan-1-one 

Downstream Products

• 91497-64-2 2-ethyl-2-phenyl-succinic acid 
• 29840-36-6 2,3-dicyano-3-phenyl-valeric acid ethyl ester 
• 20621-70-9 ethyl 2-cyano-3-phenylpentanoate 
• 14368-41-3 3-phenyl-2-pentenenitrile 
• 92300-80-6 ethyl 2-methyl-3-phenylpentanoate 
• 67246-15-5 1,1-Dichloro-2-carbethoxy-2-cyano-3-ethyl-3-phenyl-cyclopropan 
• 91391-89-8 2-ethyl-2-phenyl-succinonitrile 
• 88613-44-9 2-Aethyl-2-(4-nitro-phenyl)-bernsteinsaeure 
• 724746-07-0 6-methyl-5-phenyl-2-(pyridin-2-yl)thieno[2,3-d]pyrimidin-4(3H)-one 
• 724746-10-5 6-methyl-5-phenyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4(3H)-one 
• 724746-13-8 6-methyl-5-phenyl-2-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4(3H)-one 
• 4815-37-6 ethyl 2-amino-5-methyl-4-phenylthiophene-3-carboxylate 

Relevant articles and documents

PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE

The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease, in particular influenza.

THIENOPYRIMIDINE DERIVATIVES AS POTASSIUM CHANNEL INHIBITORS

The present invention provides thienopyrimidine compounds which are potasium channels inhibitors. Pharmaceutical compositions comprising the compounds and their use in the treatment of arrhythmia are also provided.