724746-10-5

Basic information

• Product Name: 6-methyl-5-phenyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4(3H)-one
• Synonyms: 6-methyl-5-phenyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4(3H)-one
• CAS NO: 724746-10-5
• Molecular Weight: 319.387
• Mol File: 724746-10-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methyl-5-phenyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-5-phenyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4(3H)-one(724746-10-5)
• EPA Substance Registry System: 6-methyl-5-phenyl-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4(3H)-one(724746-10-5)

Safety Data

• Hazardous Substances Data: 724746-10-5(Hazardous Substances Data)

Upstream product

• 100-54-9 pyridine-3-carbonitrile 
• 4815-37-6 ethyl 2-amino-5-methyl-4-phenylthiophene-3-carboxylate 
• 14442-48-9 (E/Z)-ethyl 2-cyano-3-phenylpent-2-enoate 
• 93-55-0 1-phenyl-propan-1-one 

Relevant articles and documents

Synthesis and antimicrobial activity of novel 2-(pyridin-2-yl)thieno[2,3-d] pyrimidin-4 (3H)-ones

In the present study, some new 2-(pyridin-2-yl)thieno[2,3-d]pyrimidin-4(3H) -ones derivatives (IIa-o) were synthesized. The target compounds (IIa-o) were synthesized through the acid catalyzed condensation of 2-cyano, 3-cyano, and 4-cyano-pyridines with various 2-amino-3-carbethoxythiophenes (Ia-e). All thiophene derivatives were synthesized by Gewald reaction. The structures of the newly synthesized compounds were confirmed by UV-Visible, FT-IR, 1H-NMR, and mass spectral studies. All synthesized compounds were evaluated for their antimicrobial activity against various gram-positive and gram-negative bacterial and fungal strains. Amongst the synthesized compounds IIa, IIb, IId, IIe, and IIm were found to be active. TUeBITAK.