144486-12-4

Basic information

• Product Name: 1-(4-(trifluoromethyl)phenyl)but-3-en-1-ol
• Synonyms: 1-(4-(trifluoromethyl)phenyl)but-3-en-1-ol
• CAS NO: 144486-12-4
• Molecular Formula: C₁₁H₁₁F₃O
• Molecular Weight: 216.201
• Mol File: 144486-12-4.mol
• Article Data: 59

Chemical Properties

• Boiling Point: 258.947 °C at 760 mmHg
• Flash Point: 112.347 °C
• Appearance: /
• Density: 1.187 g/cm³
• Vapor Pressure: 0.007mmHg at 25°C
• Refractive Index: 1.475
• CAS DataBase Reference: 1-(4-(trifluoromethyl)phenyl)but-3-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(trifluoromethyl)phenyl)but-3-en-1-ol(144486-12-4)
• EPA Substance Registry System: 1-(4-(trifluoromethyl)phenyl)but-3-en-1-ol(144486-12-4)

Safety Data

• Hazardous Substances Data: 144486-12-4(Hazardous Substances Data)

Usage

General Description

1-(4-(Trifluoromethyl)phenyl)but-3-en-1-ol is a chemical compound with the molecular formula C11H11F3O. It is an organic compound that contains a trifluoromethyl group, a phenyl group, and a but-3-en-1-ol group. 1-(4-(Trifluoromethyl)phenyl)but-3-en-1-ol is used in various industries, such as pharmaceuticals, agrochemicals, and materials science. It can be used as a building block in the synthesis of other organic compounds due to its reactivity and functional groups. Additionally, it may have potential biological and pharmacological activities that make it useful in medicinal chemistry. Overall, 1-(4-(Trifluoromethyl)phenyl)but-3-en-1-ol is a versatile compound with various applications in different fields.

InChI:InChI=1/C11H11F3O/c1-2-3-10(15)8-4-6-9(7-5-8)11(12,13)14/h2,4-7,10,15H,1,3H2

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 106-95-6 allyl bromide 
• 1730-25-2 allylmagnesium bromide 
• 107-37-9 allyltrichlorosilane 
• 2622-05-1 allylmagnesium bromide 
• 107-05-1 3-chloroprop-1-ene 
• 349-95-1 4-(trifluoromethyl)benzylic alcohol 
• 7393-43-3 tetraallyl tin 
• 591-87-7 Allyl acetate 
• 762-72-1 allyl-trimethyl-silane 
• 201164-22-9 (1S,2S)-2-(p-trifluoromethylphenyl)cyclopropylmethane 
• 201164-21-8 (1R,2R)-2-(p-trifluoromethylphenyl)cyclopropylmethane 
• 72824-04-5 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 89321-49-3 trans-1-methyl-2-(4-(trifluoromethyl)phenyl)cyclopropane 

Downstream Products

• 201164-23-0 1-(4-(trifluoromethyl)phenyl)but-3-en-1-one 
• 1322093-36-6 C₁₈H₁₈F₃NO₃S 
• 1408678-87-4 5-(chloromethyl)-3-[4-(trifluoromethyl)phenyl]-4,5-dihydroisoxazole 
• 1620206-43-0 (E)-N-(1-bromo-4-(4-(trifluoromethyl)phenyl)but-3-en-2-yl)-2,2,2-trichloroacetamide 
• 1620206-25-8 C₁₃H₁₁Cl₃F₃NO 
• 201164-24-1 (E)-1-[4-(trifluoromethyl)phenyl]-2-buten-1-one 
• 1219706-09-8 5-(4-(trifluoromethyl)phenyl)tetrahydrofuran-3-yl acetate 
• 1033605-67-2 C₁₁H₁₀ClF₃ 

Relevant articles and documents

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Ni-Catalyzed 1,2-Diarylation of Alkenyl Ketones: A Comparative Study of Carbonyl-Directed Reaction Systems

A nickel-catalyzed 1,2-diarylation of alkenyl ketones with aryl iodides and arylboronic esters is reported. Ketones with a variety of substituents serve as effective directing groups, offering high levels of regiocontrol. A representative product is diversified into a wide range of useful products that are not readily accessible via existing 1,2-diarylation reactions. Preliminary mechanistic studies shed light on the binding mode of the substrate, and Hammett analysis reveals the effect of electronic factors on initial rates.