144493-14-1

Basic information

• Product Name: Benzene, 1-methoxy-4-(1-octynyl)-
• CAS NO: 144493-14-1
• Molecular Formula: C15H20O
• Molecular Weight: 216.323
• Mol File: 144493-14-1.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-4-(1-octynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-4-(1-octynyl)-(144493-14-1)
• EPA Substance Registry System: Benzene, 1-methoxy-4-(1-octynyl)-(144493-14-1)

Safety Data

• Hazardous Substances Data: 144493-14-1(Hazardous Substances Data)

Upstream product

• 629-05-0 n-octyne 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 99-90-1 para-bromoacetophenone 
• 781645-69-0 4,4,5,5-tetramethyl-2-(oct-1-yn-1-yl)-1,3,2-dioxaborolane 
• 16967-02-5 1-phenyl-1-octyne 
• 768-60-5 4-methoxyphenylacetylen 
• 33675-41-1 1-bromo-2-(4-methoxyphenyl)acetylene 
• 137595-18-7 1-octynylzinc bromide 
• 1846-70-4 non-2-ynoic acid 
• 1950-68-1 4-methoxybenzenesulfonyl hydrazide 
• 54663-78-4 tributyl(thien-2-yl)stannane 
• 38761-67-0 1-bromo-1-octyne 

Downstream Products

• 1370521-18-8 (Z)-4-methoxy-2-(methoxymethoxy)-1-[1-(4-methoxyphenyl)oct-1-en-1-yl]benzene 
• 1370521-20-2 (Z)-4-methoxy-1-[1-(4-methoxyphenyl)oct-1-en-1-yl]-2-nitrobenzene 
• 1415913-91-5 3-(n-hexyl)-4-(4-methoxyphenyl)-6-nitropyrazolo[5,1-a]isoquinoline 
• 144492-90-0 (E)-2-Hexyl-1-(4-methoxyphenyl)-5-phenyl-1-penten-3-ol 
• 144493-05-0 (E)-4-(4-Methoxyphenyl)-1-phenyl-4-undecen-3-ol 
• 62170-25-6 1-(4-methoxyphenyl)octan-1-one 
• 121990-05-4 N-(4-methoxyphenyl)octanamide 
• 1432044-09-1 2-allyl-1-(4-methoxyphenyl)octan-1-one 
• 1432044-10-4 4-(4-methoxyphenyl)undec-1-en-5-one 
• 1243000-63-6 (E)-1-(4-methoxyphenyl)-2-phenylmethyl-1-octene 
• 1313609-72-1 C₂₂H₂₈O 

Relevant articles and documents

Copper-free Sonogashira reaction using gold nanoparticles supported on Ce2O3, Nb2O5 and SiO2 under microwave irradiation

In the present communication we wish to report a copper-free Sonogashira reaction catalyzed by gold-supported catalysts under microwave irradiation. Aryl and alkyl acetylenes were used and good yields were obtained with short reaction times when DMF was u

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The Pd-catalysed alkynylation of alkynylboronic esters (generated in situ) with various aryl chlorides in the presence of Pd2(dba)3, the sterically hindered dihydroimidazolium salt 4 as the precatalyst and CsF is reported. Under thes

Preparation anchored Pd nanoparticles on glyoxal modified metal- organic framework for Sonogashira coupling reactions

UIO-66-NH2-Gl?Pd nanocatalyst was successfully synthesized during post-synthetic modification (PSM) method and its application was investigated in the Sonogashira coupling reactions. Initially, UIO-66-NH2 was synthesized and identifi

Enhanced catalytic activity of CuI/diethoxyphosphoryl-1,10-phenanthrolines in ‘on water’ Cu-catalyzed Sonogashira reaction

The use of CuI/diethoxyphosphoryl-1,10-phenanthrolines and ‘on water’ conditions in the Cu-catalyzed Sonogashira reaction of aryl iodides with terminal alkynes significantly increases the reaction rate as compared to that in organic solvents.

Facile synthesis of Pd nanoparticles supported on a novel Schiff base modified chitosan-kaolin: Antibacterial and catalytic activities in Sonogashira coupling reaction

The present work studies the Sonogashira coupling reaction (SCR) between aryl halides and acetylenes under aerobic conditions using the catalytic complex of Pd nanoparticles (NPs) supported on a novel Schiff base modified chitosan-kaolin (Pd NPs@CS-Kao) in ethanol solvent. The prepared catalyst was characterized by TEM, SEM, FT-IR, XRD, EDS, XPS, elemental mapping, and Raman analyses. The products were formed in high yields. At the end of the reaction, Pd NPs@CS-Kao can be filtered and reused for five consecutive cycles. The advantages of this catalytic process include simple methodology, high yields, and easy work-up. In addition, Pd NPs@CS-Kao exhibited effective antibacterial performance against E. coli gram-negative bacteria.

Stereo-defined synthesis of differentially all-carbon tetrasubstituted alkenes derived from (E)-1-bromo-2-iodoalkenes

An intuitive approach to differentially all-carbon tetrasubstituted olefins from a scaffold of (E)-1-bromo-2-iodoalkenes is described. The iodine atom of the scaffold selectively undertook CuTC-mediated cross-coupling reactions with organotin reagents, suppressing a side-reaction of β-halogen elimination. The resultant vinyl bromides were successfully subjected to various transformations into tetrasubstituted olefins bearing four different carbon-linked groups. The crystallographic analysis revealed that the configuration of the double bonds is fully retained in those two steps. Thus, the template strategy would provide a new entry for preparing stereo-defined tetrasubstituted alkenes.

Copper-catalyzed Sonogashira-type reactions under mild palladium-free conditions

(Chemical Equation Presented) We have developed an inexpensive catalytic system using a readily available copper/ligand combination for the Sonogashira-type cross-coupling of aryl iodides and phenyl- and hexyl-acetylene which affords disubstituted alkynes

Pd nanoparticles loaded on modified chitosan-Unye bentonite microcapsules: A reusable nanocatalyst for Sonogashira coupling reaction

This work investigates the preparation of a catalytic complex of palladium nanoparticles supported on novel Schiff base modified chitosan-Unye bentonite microcapsules (Pd NPs@CS-UN). The complex has been characterized by FT-IR, EDS, XRD, TEM, HRTEM, Raman

Aqueous Sonogashira coupling of aryl halides with 1-alkynes under mild conditions: Use of surfactants in cross-coupling reactions

Aqueous Sonogashira coupling between lipophilic terminal alkynes and aryl bromides or iodides gave moderate to high yields at 40°C using readily available and inexpensive surfactants (2.0 w/v% in water) such as SDS and CTAB. The catalyst precursor was 2 m

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