144534-91-8

Upstream product

• 152934-39-9 (2S)-2-<(4S,5S)-5-Ethyl-2,2-dimethyl-1,2-dioxan-4-yl>propan-1-ol 
• 156479-49-1 (2S,3R,4R)-2-ethyl-1,3-isopropylidenedioxy-4-methyl-5-phenylthiopentane 
• 156479-44-6 (3R,4S,5S)-4-acetoxy-6-benzyloxymethoxy-5-methyl-3-(4-methylphenylsulfonyloxymethyl)hex-1-ene 
• 156479-45-7 (3S,4S,5S)-4-acetoxy-6-benzyloxymethoxy-3-ethyl-5-methylhex-1-ene 
• 156479-48-0 (2S,3S,4S)-1-benzyloxymethoxy-4-ethyl-3,5-isopropylidenedioxy-2-methylpentane 
• 156479-47-9 (2S,3S,4S)-5-benzyloxymethoxy-2-ethyl-4-methylpentane-1,3-diol 
• 156557-41-4 (4S)-5-benzyloxymethyloxy-2,3-epoxy-4-methylpentan-1-ol 
• 153977-33-4 (2S)-2-<(4S,5S)-5-Ethyl-2,2-dimethyl-1,2-dioxan-4-yl>-1-tosyloxypropane 
• 156479-43-5 (2S,3S,4R)-1-benzyloxymethoxy-2-methyl-4-(4-methylphenylsulfonyloxymethyl)hex-5-en-3-ol 
• 156479-42-4 (2R,3S,4S)-5-benzyloxymethoxy-4-methyl-2-vinylpentane-1,3-diol 

Downstream Products

• 144534-94-1 (2R,5S,6R,8R,9S)-3-Benzenesulfinyl-9-benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-8-ethyl-2-((4R,5S)-5-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-5-(4-methoxy-benzyloxy)-6-methyl-undecan-4-ol 
• 144535-02-4 <4R,4(2S,3S,5R),5<(2R,3R,5R),5(1S)>>-4-<5-<5-(1-benzyloxy)propyl-5-ethyl-2-hydroxy-3-methyltetrahydrofuran-2-yl>-3,5-dimethyltetrahydrofuran-2-yl>hexan-3-one 
• 144535-03-5 <4R,4(2S,3S,5R),5<(2RS,3R,5R),5(1S)>>-4-<5-<5-(1-benzyloxy)propyl-5-ethyl-2-methoxy-3-methyltetrahydrofuran-2-yl>-3,5-dimethyltetrahydrofuran-2-yl>hexan-3-one 

Relevant academic research and scientific papers

Stereoselective synthesis of optically active 4-ethyl-3,5-dihydroxy-2- methylpentyl derivatives. A basic building block with three contiguous chiral centers of polyether antibiotics

Optically active 4-ethyl-3,5-dihydroxy-2-methylpentyl derivatives, the iodide (4), phenyl sulfone (5), and phenyl sulfoxide (6), which are chiral synthons for an essential structural unit of polyether antibiotics, were stereoselectively synthesized starti

Total Synthesis of the Polyether Antibiotic Lysocellin. 2. Stereocontrolled Synthesis of the C10-C23 Fragment and Its Aldol Condensation with the C1-C9 Fragment to Complete the Total Synthesis of Lysocellin

The C10-C23 ethyl ketone (4) was synthesized via coupling of the C16-C23 aldehyde (3) with the C11-C15 fragment (8), and subjected to the aldol reaction with the C1-C9 aldehyde (2) to complete the first stereoselective synthesis of the polyether antibioti