1445434-24-1

Basic information

• Product Name: N-((4-fluorophenyl)(phenyl)methyl)pyridin-2-amine
• CAS NO: 1445434-24-1
• Molecular Weight: 278.329
• Mol File: 1445434-24-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-((4-fluorophenyl)(phenyl)methyl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-((4-fluorophenyl)(phenyl)methyl)pyridin-2-amine(1445434-24-1)
• EPA Substance Registry System: N-((4-fluorophenyl)(phenyl)methyl)pyridin-2-amine(1445434-24-1)

Safety Data

• Hazardous Substances Data: 1445434-24-1(Hazardous Substances Data)

Upstream product

• 4589-12-2 N-(pyrid-2-yl)benzamide 
• 5223-01-8 2-phenyl-N-(pyridin-2-yl)acetamide 
• 96354-74-4 N-(diphenylmethyl)pyridin-2-amine 
• 74037-48-2 N-(1,2-diphenylethyl)pyridin-2-amine 
• 923748-45-2 N-(pyridin-2-yl)monomethyl terephthalate monoamide 
• 456-22-4 4-Fluorobenzoic acid 
• 325-97-3 4-fluoro-N-(pyridine-2-yl)benzamide 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 100-58-3 phenylmagnesium bromide 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 245-47-6 benzo[4,5]imidazo[1,2-a]pyridine 
• 136343-75-4 8-fluoropyrido[1,2-a]benzimidazole 

Relevant articles and documents

Ruthenium-Catalyzed Reductive Arylation of N-(2-Pyridinyl)amides with Isopropanol and Arylboronate Esters

A new three-component reductive arylation of amides with stable reactants (iPrOH and arylboronate esters), making use of a 2-pyridinyl (Py) directing group, is described. The N-Py-amide substrates are readily prepared from carboxylic acids and PyNH2, and the resulting N-Py-1-arylalkanamine reaction products are easily transformed into the corresponding chlorides by substitution of the HN-Py group with HCl. The 1-aryl-1-chloroalkane products allow substitution and cross-coupling reactions. Therefore, a general protocol for the transformation of carboxylic acids into a variety of functionalities is obtained. The Py-NH2 by-product can be recycled.