144582-53-6

Basic information

• Product Name: (E)-3-[2-(2,2-Dimethyl-propionyloxy)-4-methoxy-phenyl]-acrylic acid methyl ester
• CAS NO: 144582-53-6
• Molecular Weight: 292.332
• Mol File: 144582-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-[2-(2,2-Dimethyl-propionyloxy)-4-methoxy-phenyl]-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-[2-(2,2-Dimethyl-propionyloxy)-4-methoxy-phenyl]-acrylic acid methyl ester(144582-53-6)
• EPA Substance Registry System: (E)-3-[2-(2,2-Dimethyl-propionyloxy)-4-methoxy-phenyl]-acrylic acid methyl ester(144582-53-6)

Safety Data

• Hazardous Substances Data: 144582-53-6(Hazardous Substances Data)

Upstream product

• 144582-47-8 methyl 2'-acetoxy-4'-methoxycinnamate 
• 531-59-9 7-methoxycoumarin 
• 93198-68-6 (E)-methyl 2’-hydroxy-4’-methoxycinnamate 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 117285-73-1 methyl 3-(4-methoxy-2-pivaloyloxyphenyl)propanoate 

Relevant articles and documents

EFFICIENT, HIGHLY REGIOSELECTIVE FRIES REARRANGEMENTS OF METHYL 3-(2-ACYLOXY-4-METHOXYPHENYL)PROPANOATES: THE FIRST TOTAL SYNTHESIS OF THE LINEAR ACYLATED COUMARINS GEIJERIN AND DEHYDROGEIJERIN.

Aluminium chloride catalysed para-Fries rearrangement of methyl 3-(2-acyloxy-4-methoxyphenyl)propanoates (5) in nitromethane furnishes the corresponding 5-acylated products (6) cleanly and in high yield.The rearrangement products may be converted into 6-a