144584-07-6

Upstream product

• 64018-25-3 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctanoyl chloride 
• 118-92-3 anthranilic acid 
• 53826-12-3 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctanoic acid 
• 647-42-7 1H,1H,2H,2H-tridecafluoro-n-octanol 

Relevant academic research and scientific papers

Synthesis of 2-[(Z)-1-hydropolyfluoro-1-alkenyl]-4H-3,1-benzoxazin-4-ones

N,N′-dicyclohexylcarbodiimide induced condensation of 2,2-dihydropolyfluoroalkanoic acid and anthranilic acid or its derivatives followed by a dehydrating ring-closure reaction in the presence of Ac2O gave 2-[(Z)-1-hydropolyfluoro-1-alkenyl]-4H-3,1-benzoxazin-4-ones in good to excellent yields.

Etude du comportement de benzoxazinones, substituees en position 2 par des groupements (per)halogenes, vis-a-vis de l'aniline

This study describes firstly the synthesis of benzoxazinones substituted in position 2 by halogenated groups such as -(CH2)n-RF,Cl where n=0, 1 and 2 and RF,Cl is a perhalogenated group, and secondly the reaction of these new benzoxazinones with aniline in different media.Thus it is shown that the behaviour of trifluoromethyl-2-benzoxazinone towards aniline is different, in most cases, in comparison with benzoxazinones substituted by perfluorinated groups CnF2n+1 with n=2, 3 and 7.Under certain conditions (hot ethanol and aniline with triphenyl phosphite), it is observed that nucleophilic attack of aniline only occurs on the carbonyl group when benzoxazinones are substituted by an electron-withdrawing group such as C2F5, C3F7 and C7F15.