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N-ACETYL-L-GLUTAMIC ACID DIETHYL ESTER is a chemical compound derived from the amino acid L-glutamic acid, featuring a diethyl ester structure with two ethyl groups attached to the carboxyl group. It serves as a versatile building block in organic chemistry and is extensively utilized in the synthesis of pharmaceuticals.

1446-19-1

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1446-19-1 Usage

Uses

Used in Pharmaceutical Synthesis:
N-ACETYL-L-GLUTAMIC ACID DIETHYL ESTER is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, N-ACETYL-L-GLUTAMIC ACID DIETHYL ESTER is used as a building block for the construction of complex organic molecules, facilitating the creation of novel chemical compounds with potential applications in various industries.
Used as a Reagent in Organic Synthesis:
N-ACETYL-L-GLUTAMIC ACID DIETHYL ESTER is employed as a reagent in organic synthesis, enabling chemists to perform specific reactions and transformations, which are essential for the synthesis of target molecules.
Used in Medical and Research Applications:
Although its primary application lies in chemical synthesis, N-ACETYL-L-GLUTAMIC ACID DIETHYL ESTER can also be used as a supplement in certain medical and research applications, supporting scientific investigations and potentially contributing to advancements in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 1446-19-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,4 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1446-19:
(6*1)+(5*4)+(4*4)+(3*6)+(2*1)+(1*9)=71
71 % 10 = 1
So 1446-19-1 is a valid CAS Registry Number.

1446-19-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name diethyl (2S)-2-acetamidopentanedioate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1446-19-1 SDS

1446-19-1Relevant academic research and scientific papers

Regioselective lipase-catalyzed synthesis of L-glutamic α-monoamide derivatives. Effect of the N-blocking group

Conde, Santiago,Lopez-Serrano, Paloma,Fierros, Marta,Biezma, Maria Isabel,Martinez, Ana,Rodriguez-Franco, Maria Isabel

, p. 11745 - 11752 (1997)

Several Block-L-Glu(OEt)-OEt (Block = amides, carbamates and trityl group) have been subjected to an aminolysis reaction catalyzed by the lipase B of Candida antarctica. The reaction took place in a regioselcctive manner and α-monoamides were obtained in all cases (except the bulky trityl group that did not react). Besides (he synthetic value of the method, the results may empirically point out to some features of tile active site of the enzyme as the reaction rate was severely affected by volume and electronic characteristics of the blocking group.

A Simple and Efficient Esterification Method

Ming-Yi, Chen,Lee, Adam Shih-Yuan

, p. 103 - 108 (2007/10/03)

A convenient and practical esterification was realized and this reaction proceeded without a dehydrating reagent or water removal equipment. The synthesis of esters by reaction of carboxylic acids with various alcohols such as methyl, ethyl, isopropyl, isobutyl, allyl, benzyl, propargyl and decanyl alcohols were achieved with a catalytic amount of CBr4 under refluxing reaction condition.

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