1446266-64-3

Upstream product

• 1279845-56-5 2-amino-5-[(1-bromo-2-methylindolizin-3-yl)carbonyl]benzoic acid 
• 5680-79-5 glycine ethyl ester hydrochloride 

Downstream Products

• 1446266-69-8 methyl [6-({1-[4-(2-tert-butoxy-2-oxoethoxy)phenyl]-2-methylindolizin-3-yl}carbonyl)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]acetate 
• 1446266-70-1 [4-(3-{[3-(2-methoxy-2-oxoethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-6-yl]carbonyl}-2-methylindolizin-1-yl)phenoxy]acetic acid 

Relevant academic research and scientific papers

FGF RECEPTOR (FGFR) AGONIST DIMERIC COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The invention relates to novel heterocyclic compounds which are pyrazolopyridine derivatives that induce FGFR dimerization, having the general formula: M -L-M 2 in which M and M 2, which may be identical or different, each represent, independently of one another, a monomer unit Mand L represents a linker group which links M1 and M2 covalently with the monomer unit which follows (Formula M). Process for the preparation thereof and therapeutic use thereof.