1446320-20-2

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 64-19-7 acetic acid 
• 70934-09-7 2-amino-6,7,8,9-tetrahydro-11Hpyrido[2,1-b]quinazolin-11-one 
• 98832-57-6 N-(11-oxo-6,8,9,11-tetrahydro-7H-pyrido[2,1-b]quinazolin-2-yl)acetamide 
• 2446-62-0 7,8,9-trihydropyrido[2,1-b]quinazolin-11(6H)-one 
• 64842-92-8 2-Nitro-6,7,8,9-tetrahydro-11H-pyrido<2,1-b>quinazolin-11-one 

Relevant academic research and scientific papers

Synthesis of 8-amino- and 8-acetyl(benzoyl) aminomackinazolinones and their condensation with aldehydes

Methods for preparing of 8-nitro- and 8-aminomackinazolinones were improved. 8-Acetyl(benzoyl)aminomackinazolinones reacted smoothly with aromatic aldehydes and furfurol in glacial acetic acid to give the corresponding 4-arylidene-substituted derivatives. Reaction of 8-aminomackinazolinone with aromatic aldehydes in glacial acetic acid was accompanied by acetylation of the amine and gave 8-acetylamino-4-arylidenemackinazolinones. Reaction of 8-aminomackinazolinone and p-nitrobenzaldehyde in propionic acid produced 8-[(4' -nitrobenzylidene)amino]-4-(4'-nitrobenzylidene)mackinazolinone. In contrast, the reaction in Py occurred selectively at the amine to form the corresponding Schiff base 8-[(4'-nitrobenzylidene)amino]mackinazolinone.