14464-10-9Relevant academic research and scientific papers
AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE
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Paragraph 0403, (2016/08/17)
The present invention provides amino ester compounds, salts, and pharmaceutical formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating inter- and/or intra-cellular signaling. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.
NOVEL COMPOUNDS
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Page/Page column 61; 62, (2015/12/17)
Disclosed are novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.
ANGIOTENSIN II RECEPTOR ANTAGONISTS
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Page/Page column 22, (2009/12/23)
A compound having the structure wherein R is, for example, Y is selected from the group consisting of 1) R5, 2) -C(R1R2)(C(R3R4))0-1Y1R5, and 3) -C(R1R2)-O-Y1R5; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-4 alkyl; R5 is; Y1 is selected from the group consisting of C(O)-O- and P(O)(OR6)-O-; and R6 is hydrogen or CH3, or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension.
Amino-acids and peptides. Part VI. The synthesis, by twinning, of cyclodepsipeptides related to serratamolide
Hassall,Martin,Schofield,Thomas, Jean O.
, p. 997 - 1003 (2007/10/10)
A fourteen-membered cyclodepsipeptide has been synthesised by the interaction of two molecules of β-L-leucyloxy-propionyl chloride. A similar synthesis utilising β-(O-t-butyl-DL-seryloxy)propionyl chloride gave two isomers. The relationship of these isomers has been discussed.
