144665-41-8Relevant academic research and scientific papers
Highly stereoselective syntheses of all 1,2,3-Me,OH,Me triads via asymmetric hydrogenation reactions
Zhu, Ye,Burgess, Kevin
, p. 107 - 115 (2013/03/14)
Iridium-catalyzed asymmetric hydrogenations of chiral alkenes were used to access four pivotal α,ω-functionalized chirons, that contain widely occurring stereochemical 1,2,3-Me,OH,Me motifs. A chiral analogue of Crabtree's catalyst was used in key hydrogenation steps to form these motifs with high stereochemical purities. An application of one of these chirons is illustrated here with a synthesis of (-)-invictolide. Copyright
Total synthesis of the ionophore antibiotic CP-61,405 (routiennocin)
Diez-Martin, David,Kotecha, Nikesh R.,Ley, Steven V.,Mantegani, Sergio,Menendez, J. Carlos,Organ, Helen M.,White, Andrew D.,Banks, Bernard J.
, p. 7899 - 7938 (2007/10/02)
The total synthesis of the spiroketal ionophore antibiotic routiennocin 1 (CP-61,405) employing π-allyltricarbonyl iron lactone complexes is described. These complexes were used as precursors for the preparation of substituted 2-phenylsulphonyl pyrans whi
