91550-14-0Relevant academic research and scientific papers
Total synthesis of attenols A and B
Reddy, B.V. Subba,Reddy, B. Phaneendra,Swapnil,Yadav
, p. 5781 - 5784 (2013/10/01)
A concise approach for the total synthesis of attenols A and B is described involving MacMillan's α-aminooxylation, Evan's asymmetric alkylation, Brown's allylation, and spiro-ketalization as key steps. This approach has successfully demonstrated the α-aminooxylation protocol for the construction of the anti-1,3-diol unit.
Synthetic studies on maitotoxin. 1. Stereoselective synthesis of the C D E F -ring system having a side chain
Morita, Masayuki,Ishiyama, Seishi,Koshino, Hiroyuki,Nakata, Tadashi
supporting information; experimental part, p. 1675 - 1678 (2009/04/10)
The stereoselective synthesis of the maitotoxin C D E F -ring system having a side chain has been accomplished through a convergent strategy. The key reactions include Horner-Wadsworth-Emmons coupling of the C D E -ring and the side chain and subsequent c
A total synthesis of the unique tris-oxazole macrolide ulapualide a produced by the marine nudibranch Hexabranchus sanguineus
Chattopadhyay, Shital K.,Pattenden, Gerald
, p. 2429 - 2454 (2007/10/03)
A total synthesis of ulapualide A (1), whose relative stereochemistry was assigned on the basis of an earlier molecular mechanics study of its hypothetical metal chelated complex 9, is described. The synthesis is based on: i, elaboration of the double fun
Synthetic studies towards novel tris-oxazole based macrolides of marine origin. Stereocontrolled synthesis of the C20 - C35 fragment in ulapualide A
Chattopadhyay, Shital K.,Pattenden, Gerald
, p. 5271 - 5274 (2007/10/02)
The C20 - C35 subunit 3 in ulapualide A 1 has been synthesised in enantiomerically pure form using a combination of the Evans aldol reaction, controlled ring opening reactions of chiral epoxides, and Brown's asymmetric allylboration reaction, to set up th
Studies directed towards the synthesis of rapamycin: Stereoselective synthesis of C-1 to C-15 segment
Rama Rao,Desibhatla, Vidyanand
, p. 7111 - 7114 (2007/10/02)
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described.
The First Enantioselectice Total Syntheses of the Allopumiliotoxin A Alkaloids 267A and 339B
Goldstein, Steven W.,Overmann, Larry E.,Rabinowitz, Michael H.
, p. 1179 - 1190 (2007/10/02)
Short, highly stereocontrolled, asymmetric total syntheses of the title amphibian alkaloids are described.In the first stage the indolizidine ketone 11 is assembled from L-proline in enantiomerically pure form.This short sequence proceeds in five laborato
BIFUNCTIONAL CHIRAL SYNTHONS VIA BIOCHEMICAL METHODS. VI. C5 ISOPRENOID UNITS.
VanMiddlesworth, Frank,Wang, Yi Fong,Zhou, Bing-nan,DiTullio, Dennis,Sih, C. J.
, p. 961 - 964 (2007/10/02)
Two methods for the preparation of the isoprenoid chiron 4 have been developed using a microbial kinetic resolution of 5 and an enantiotopically selective hydrolysis of 7 catalyzed by PLE.
