443752-42-9

Basic information

• Product Name: [4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-2-oxo-butyl]-phosphonic acid diethyl ester
• Synonyms: [4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-2-oxo-butyl]-phosphonic acid diethyl ester
• CAS NO: 443752-42-9
• Molecular Weight: 490.652
• Mol File: 443752-42-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-2-oxo-butyl]-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-2-oxo-butyl]-phosphonic acid diethyl ester(443752-42-9)
• EPA Substance Registry System: [4-(tert-butyl-diphenyl-silanyloxy)-1,3-dimethyl-2-oxo-butyl]-phosphonic acid diethyl ester(443752-42-9)

Safety Data

• Hazardous Substances Data: 443752-42-9(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 78-38-6 ethylphosphonic acid diethyl ester 
• 95514-03-7 (R)-methyl 3-(tert-butyl(diphenyl)silyloxy)-2-methylpropanoate 

Downstream Products

• 144604-69-3 <4S,5R,(R)>-4-<4-(benzyloxy)butyl>-2,2,5-trimethyl-1,3-dioxane 
• 1452816-26-0 (2R,3S,4S)-6-(benzyloxy)-1-[(tert-butyldiphenylsilyl)-oxy]-2,4-dimethylhexan-3-ol 
• 1452816-25-9 (2R,3S)-E-6-(benzyloxy)-1-[(tert-butyldiphenylsilyl)-oxy]-2,4-dimethylhex-4-en-3-yl acetate 
• 943858-49-9 C₁₅H₂₄O₃ 
• 1452816-24-8 (2R,3S)-E-6-(benzyloxy)-1-[(tert-butyldiphenylsilyl)-oxy]-2,4-dimethylhex-4-en-3-ol 
• 1452816-23-7 (2R,3S)-E-6-(benzyloxy)-2,4-dimethylhex-4-ene-1,3-diol 
• 1452816-22-6 (R)-E-6-(benzyloxy)-1-hydroxy-2,4-dimethylhex-4-en-3-one 
• 144665-41-8 C₁₅H₂₄O₃ 
• 1452816-21-5 (2R,3R)-E-6-(benzyloxy)-2,4-dimethylhex-4-ene-1,3-diol 
• 1452816-20-4 (2R,3R)-E-6-(benzyloxy)-1-[(tert-butyldiphenylsilyl)-oxy]-2,4-dimethylhex-4-en-3-ol 
• 1452816-28-2 (2R,3R,4R)-6-(benzyloxy)-1-[(tert-butyldiphenylsilyl)-oxy]-2,4-dimethylhexan-3-ol 
• 1452816-27-1 (2R,3R,4S)-6-(benzyloxy)-1-[(tert-butyldiphenylsilyl)-oxy]-2,4-dimethylhexan-3-ol 
• 1452816-19-1 (R)-E-6-(benzyloxy)-1-[(tert-butyldiphenylsilyl)oxy]-2,4-dimethylhex-4-en-3-one 
• 443752-44-1 (2R,3R,5R,6R)-1-(tert-Butyl-diphenyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2,6-dimethyl-4-methylene-heptane-3,5-diol 

Relevant articles and documents

Highly stereoselective syntheses of all 1,2,3-Me,OH,Me triads via asymmetric hydrogenation reactions

Iridium-catalyzed asymmetric hydrogenations of chiral alkenes were used to access four pivotal α,ω-functionalized chirons, that contain widely occurring stereochemical 1,2,3-Me,OH,Me motifs. A chiral analogue of Crabtree's catalyst was used in key hydrogenation steps to form these motifs with high stereochemical purities. An application of one of these chirons is illustrated here with a synthesis of (-)-invictolide. Copyright