1447331-32-9

Basic information

• Product Name: {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid methyl ester
• Synonyms: {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid methyl ester
• CAS NO: 1447331-32-9
• Molecular Weight: 508.574
• Mol File: 1447331-32-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid methyl ester(1447331-32-9)
• EPA Substance Registry System: {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid methyl ester(1447331-32-9)

Safety Data

• Hazardous Substances Data: 1447331-32-9(Hazardous Substances Data)

Upstream product

• 39221-42-6 (1-oxo-1,3-dihydro-2H-isoindol-2-yl)carboxylic acid 
• 1146295-07-9 (6-nitro-1-oxo-1,3-dihydroisoindol-2-yl)acetic acid methyl ester 
• 162046-66-4 4-(4-(1,1-dimethylethoxycarbonyl)piperazin-1-yl)benzoic acid 
• 1146295-08-0 (6-amino-1-oxo-1,3-dihydroisoindol-2-yl)acetic acid methyl ester 
• 158985-36-5 4-(4-methoxycarbonyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 619-45-4 4-methoxycarbonyl aniline 
• 163210-97-7 methyl 4-(piperazin-1-yl)benzoate 
• 694499-69-9 (6-nitro-1-oxo-1,3-dihydro-2-isoindol-2-yl)acetic acid 
• 4702-13-0 N-phthaloylglycine 

Downstream Products

• 1447331-89-6 {6-[4-(4-boc-piperazin-1-yl)benzoylamino]-1-oxo-1,3-dihydroisoindol-2-yl}acetic acid 
• 1447330-19-9 [1-oxo-6-(4-piperazinium-1-yl-benzoylamino)-1,3-dihydroisoindol-2-yl]acetic acid trifluoroacetate 

Relevant articles and documents

Synthesis, biological evaluation, X-ray molecular structure and molecular docking studies of RGD mimetics containing 6-amino-2,3-dihydroisoindolin-1-one fragment as ligands of integrin αiIbβ3

A series of novel RGD mimetics containing phthalimidine fragment was designed and synthesized. Their antiaggregative activity determined by Born's method was shown to be due to inhibition of fibrinogen binding to αIIbβ3. Molecular docking of RGD mimetics to αIIbβ3 receptor showed the key interactions in this complex, and also some correlations have been observed between values of biological activity and docking scores. The single crystal X-ray data were obtained for five mimetics.