1447607-89-7

Basic information

• Product Name: tert-butyl 5-broMo-1-Methyl-1H-pyrazol-3-ylcarbaMate
• Synonyms: tert-butyl 5-broMo-1-Methyl-1H-pyrazol-3-ylcarbaMate
• CAS NO: 1447607-89-7
• Molecular Formula: C9H14BrN3O2
• Molecular Weight: 276.13036
• Mol File: 1447607-89-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 5-broMo-1-Methyl-1H-pyrazol-3-ylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 5-broMo-1-Methyl-1H-pyrazol-3-ylcarbaMate(1447607-89-7)
• EPA Substance Registry System: tert-butyl 5-broMo-1-Methyl-1H-pyrazol-3-ylcarbaMate(1447607-89-7)

Safety Data

• Hazardous Substances Data: 1447607-89-7(Hazardous Substances Data)

Usage

General Description

Tert-butyl 5-bromo-1-methyl-1H-pyrazol-3-ylcarbamate is a chemical compound with the molecular formula C10H17BrN4O2. It is a carbamate derivative of 5-bromo-1-methyl-1H-pyrazol-3-ylcarboxylic acid, with a tert-butyl group attached to the nitrogen atom of the carbamate group. tert-butyl 5-broMo-1-Methyl-1H-pyrazol-3-ylcarbaMate is used in chemical research and drug development, particularly in the synthesis of pharmaceutical compounds. It may have biological activity and has potential applications in medicinal chemistry, although further research is needed to fully understand its properties and potential uses.

Upstream product

• 1222174-93-7 5-bromo-1-methyl-1H-pyrazole-3-carboxylic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 75-65-0 tert-butyl alcohol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 89088-55-1 5-bromo-1-methyl-1H-pyrazol-3-amine 

Downstream Products

• 89088-55-1 5-bromo-1-methyl-1H-pyrazol-3-amine 

Relevant articles and documents

Synthesis method of 5-bromine-1-methyl-1H-pyrazole-3-amine

The invention discloses a synthesis method of 5-bromine-1-methyl-1H-pyrazole-3-amine. The method comprises the steps of condensing diethyl butynedioate serving as a raw material with methylhydrazine to obtain 5-hydroxyl-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester, and reacting the 5-hydroxyl-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester with phosphorus oxybromide to obtain 5-bromine-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester; hydrolyzing in a sodium hydroxide alcohol solution to obtain 5-bromine-1-methyl-1H-pyrazole-3-carboxylic acid, reacting the 5-bromine-1-methyl-1H-pyrazole-3-carboxylic acid with dimethyl azide phosphate and tert-butyl alcohol to obtain tert-butyl (5-bromine-1-methyl-1H-pyrazole-3-yl) carbamate, and hydrolyzing in trifluoroacetic acid to obtain the5-bromine-1-methyl-1H-pyrazole-3-amine. The method has the advantages of simple synthesis route, reasonable process selection, low raw material cost, simple and easily available raw materials, convenient operation and post-treatment, and no use of highly toxic reagents, and overcomes the defects of expensive and unavailable raw materials, unsafe operation, difficult amplification and the like in the existing synthesis process.