1448428-05-4

Basic information

• Product Name: Selonsertib HCl salt, GS-4997 HCl salt
• Synonyms: Selonsertib HCl salt, GS-4997 HCl salt;5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-[6-(4-isopropyl-4H-1,2,4-triazol-3-yl)-2-pyridinyl]-4-methylbenzamide hydrochloride (1:1);GS-4997 HCl salt
• CAS NO: 1448428-05-4
• Molecular Formula: C₂₄H₂₄FN₇O*ClH
• Molecular Weight: 481.96
• Mol File: 1448428-05-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Selonsertib HCl salt, GS-4997 HCl salt(CAS DataBase Reference)
• NIST Chemistry Reference: Selonsertib HCl salt, GS-4997 HCl salt(1448428-05-4)
• EPA Substance Registry System: Selonsertib HCl salt, GS-4997 HCl salt(1448428-05-4)

Safety Data

• Hazardous Substances Data: 1448428-05-4(Hazardous Substances Data)

Upstream product

• 5584-18-9 6-aminopyridine-2-carbohydrazide 
• 36052-26-3 methyl 6-aminopyridine-2-carboxylate 
• 1448427-99-3 6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-amine 
• 1448428-03-2 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methylbenzoic acid hydrochloride 
• 1448428-02-1 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methylbenzonitrile 
• 1448428-01-0 5-(4-cyclopropyl-2-mercapto-1H-imidazol-1-yl)-2-fluoro-4-methylbenzonitrile 
• 1448428-00-9 5-((2-cyclopropyl-2-oxoethyl)amino)-2-fluoro-4-methylbenzonitrile 
• 1426136-04-0 5-amino-2-fluoro-4-methylbenzonitrile 
• 627871-16-3 5-bromo-4-fluoro-2-methylaniline 

Relevant articles and documents

APOPTOSIS SIGNAL-REGULATING KINASE INHIBITOR

The present invention relates to a compound of formula (I): The compound has apoptosis signal-regulating kinase (“ASK1”) inhibitory activity, and is thus useful in the treatment of diseases such as kidney disease, diabetic nephropathy and kidney fibrosis.