1448527-72-7

Basic information

• Product Name: (+)-5-(3’,4’,5’-trimethoxyphenyl)-8,10,10-trimethyl-6-azatricyclo[7.1.1.02,7]undeca-2(7),3,5-triene
• Synonyms: (+)-5-(3’,4’,5’-trimethoxyphenyl)-8,10,10-trimethyl-6-azatricyclo[7.1.1.02,7]undeca-2(7),3,5-triene
• CAS NO: 1448527-72-7
• Molecular Weight: 353.461
• Mol File: 1448527-72-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-5-(3’,4’,5’-trimethoxyphenyl)-8,10,10-trimethyl-6-azatricyclo[7.1.1.02,7]undeca-2(7),3,5-triene(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-5-(3’,4’,5’-trimethoxyphenyl)-8,10,10-trimethyl-6-azatricyclo[7.1.1.02,7]undeca-2(7),3,5-triene(1448527-72-7)
• EPA Substance Registry System: (+)-5-(3’,4’,5’-trimethoxyphenyl)-8,10,10-trimethyl-6-azatricyclo[7.1.1.02,7]undeca-2(7),3,5-triene(1448527-72-7)

Safety Data

• Hazardous Substances Data: 1448527-72-7(Hazardous Substances Data)

Upstream product

• 7785-26-4 (-)-α-pinene 
• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 19890-00-7 (1S)-pinocarvone 
• 1448527-69-2 (+)-5-(3’,4’,5’-trimethoxyphenyl)-10,10-dimethyl-6-azatricyclo[7.1.1.02,7]undeca-2(7),3,5-triene 
• 74-88-4 methyl iodide 

Downstream Products

• 1448527-32-9 (+)-5-(3’,4’,5’-trimethoxyphenyl)-8,10,10-trimethyl-6-azatricyclo[7.1.1.02,7]undeca-2,4,6-triene 6-oxide 

Relevant articles and documents

Mechanistic dichotomy in the asymmetric allylation of aldehydes with allyltrichlorosilanes catalyzed by chiral pyridine N-oxides

Detailed kinetic and computational investigation of the enantio- and diastereoselective allylation of aldehydes 1 with allyltrichlorosilanes 5, employing the pyridine N-oxides METHOX (9) and QUINOX (10) as chiral organocatalysts, indicate that the reaction can proceed through a dissociative (cationic) or associative (neutral) mechanism: METHOX apparently favors a pentacoordinate cationic transition state, while the less sterically demanding QUINOX is likely to operate via a hexacoordinate neutral complex. In both pathways, only one molecule of the catalyst is involved in the rate- and selectivity-determining step, which is supported by both experimental and computational data. Copyright