1448782-04-4Relevant articles and documents
Asymmetric Br?nsted acid catalyzed cycloadditions-efficient enantioselective synthesis of pyrazolidines, pyrazolines, and 1,3-diamines from N-acyl hyrazones and alkenes
Rueping, Magnus,Maji, Modhu Sudan,Kü?ük, Hatice Ba?pínar,Atodiresei, Iuliana
, p. 12864 - 12868 (2013/02/22)
A general, metal-free, highly enantioselective Bronsted acid catalyzed [3+2] cycloaddition between hydrazones and alkenes has been developed that affords pyrazolidine derivatives (see scheme). The resulting optically active pyrazolidines can undergo many chemical transformations which allow, for example, the enantioselective synthesis of valuable pyrazolines and 1,3-diamines. Copyright