1448902-18-8 Usage
Uses
Used in Pharmaceutical Industry:
(1R)-1-(4-chlorophenyl)propan-1-amine hydrochloride is used as a precursor in the synthesis of other important organic compounds for the development of new pharmaceutical drugs. Its structural properties allow it to exhibit various biological activities, making it a valuable compound for scientific research and application in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 1448902-18-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,8,9,0 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1448902-18:
(9*1)+(8*4)+(7*4)+(6*8)+(5*9)+(4*0)+(3*2)+(2*1)+(1*8)=178
178 % 10 = 8
So 1448902-18-8 is a valid CAS Registry Number.
1448902-18-8Relevant academic research and scientific papers
Synthesis and optimization of novel (3S,5R)-5-(2,2-dimethyl-5-oxo-4- phenylpiperazin-1-yl)piperidine-3-carboxamides as orally active renin inhibitors
Mori, Yutaka,Ogawa, Yasuyuki,Mochizuki, Akiyoshi,Nakamura, Yuji,Fujimoto, Teppei,Sugita, Chie,Miyazaki, Shojiro,Tamaki, Kazuhiko,Nagayama, Takahiro,Nagai, Yoko,Inoue, Shin-Ichi,Chiba, Katsuyoshi,Nishi, Takahide
, p. 5907 - 5922 (2013/09/12)
We report synthesis and optimization of a series of (3S,5R)-5-(2,2- dimethyl-5-oxo-4-phenylpiperazin-1-yl)piperidine-3-carboxamides as renin inhibitors. Chemical modification of P1, P2 and P 3 portions led to a promising 3