1449029-97-3

Upstream product

• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 18234-41-8 5-(benzyloxy)-4-oxo-4H-pyran-2-carbaldehyde 
• 931-53-3 Cyclohexyl isocyanide 
• 106-47-8 4-chloro-aniline 
• 118-91-2 ortho-chlorobenzoic acid 
• 15771-06-9 5-benzyloxy-2-hydroxymethyl-4H-pyran-4-one 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction

Fourteen novel bis-carboxamide derivatives of 4-pyrones were designed and synthesized via Ugi four-component reactions of 4-pyrone carbaldehydes, aromatic amines, isocyanides and carboxylic acids. The cytotoxic activity of synthesized derivatives was eval