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1449401-87-9 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1449401-87-9

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1449401-87-9 Usage

Type of compound

Synthetic organic molecule

Target enzyme

PARP-1 (poly (ADP-ribose) polymerase-1)

Enzyme function

Key role in DNA repair

Therapeutic potential

Potent and selective inhibitor of PARP-1

Cancer treatment

Promising potential as a therapeutic agent for the treatment of cancer

Combination therapies

Effective when used in combination with other DNA-damaging treatments such as chemotherapy or radiation therapy

Other disease applications

Investigated for potential use in the treatment of inflammatory and neurodegenerative disorders

Mechanism of action

Modulates the cellular response to DNA damage

Ongoing research

Further research is being conducted to explore the full potential of 1449401-87-9 in a variety of therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1449401-87-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,9,4,0 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1449401-87:
(9*1)+(8*4)+(7*4)+(6*9)+(5*4)+(4*0)+(3*1)+(2*8)+(1*7)=169
169 % 10 = 9
So 1449401-87-9 is a valid CAS Registry Number.

1449401-87-9Downstream Products

1449401-87-9Relevant academic research and scientific papers

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF

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Paragraph 0148-0152; 0157; 0162, (2021/02/16)

An object of the present invention is to provide a compound capable of improving high luminous efficiency, low driving voltage and lifespan of a device, an organic electric element using the same, and an electronic device thereof. The present invention provides the compound represented by any one of chemical formulas 6 to 9. By using the compound according to the present invention, high luminous efficiency and low driving voltage of the device can be achieved, and the lifespan of the device can be greatly improved.

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

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, (2019/03/15)

A compound useful as a host material in phosphorescent light emitting devices is disclosed. The compound has the following formula: in which R represents an adjacent di-substitution having the following formula fused to ring A:

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF

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Paragraph 0151; 0152; 0157, (2016/10/07)

The purpose of the present invention is to provide a compound which is capable of having high light-emitting efficiency of an element, having a low driving voltage, and improving durability; an organic electronic element using the same; and an electronic device thereof. The compound is represented by chemical formula 1.(110) Substrate(120) Positive electrode(130) Hole injection layer(140) Hole transport layer(141) Buffer layer(150) Light emitting layer(151) Light-emitting assisting layer(160) Electron transport layer(170) Electron injection layer(180) Negative electrodeCOPYRIGHT KIPO 2016

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