1449416-84-5

Basic information

• Product Name: 4,4'-(but-3-en-1-yne-1,3-diyl)bis(fluorobenzene)
• Synonyms: 4,4'-(but-3-en-1-yne-1,3-diyl)bis(fluorobenzene)
• CAS NO: 1449416-84-5
• Molecular Weight: 240.252
• Mol File: 1449416-84-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4,4'-(but-3-en-1-yne-1,3-diyl)bis(fluorobenzene)(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-(but-3-en-1-yne-1,3-diyl)bis(fluorobenzene)(1449416-84-5)
• EPA Substance Registry System: 4,4'-(but-3-en-1-yne-1,3-diyl)bis(fluorobenzene)(1449416-84-5)

Safety Data

• Hazardous Substances Data: 1449416-84-5(Hazardous Substances Data)

Upstream product

• 766-98-3 1-ethynyl-4-fluorobenzene 
• 7223-38-3 N,N-Dimethylpropargylamin 
• 352-34-1 4-fluoro-1-iodobenzene 
• 130995-12-9 1-(4-fluorophenyl)-2-trimethylsilylacetylene 

Relevant articles and documents

Iron-Catalyzed gem-Specific Dimerization of Terminal Alkynes

We report a gem-specific homo- and cross-dimerization of terminal alkynes catalyzed by a well-defined iron(II) complex containing Cp* and picolyl N-heterocyclic carbene (NHC) ligands, and featuring a piano-stool structure. This catalytic system requires n

Stereo- A nd regioselective dimerization of alkynes to enynes by bimetallic syn-carbopalladation

Enynes are important motifs in bioactive compounds. They can be synthesized by alkynea'alkyne couplings for which a number of mechanisms have been suggested depending on catalyst type and dominant product isomers. Regarding bimetallic pathways, hydrometalations and anti-carbopalladations have been discussed to account for the formation of geminally substituted and (Z)-configured enynes, respectively. Here we report a bimetallic alkynea'alkyne coupling that yields (E)-configured enynes. An unusual type of acetylide Pd bridging was found in putative catalytic intermediates which is arguably responsible for the regio- A nd stereochemical reaction outcome. Mechanistic studies suggest that a double μa'κ:η2 acetylide bridging enables a bimetallic syn-carbometalation. Interestingly, depending on the reaction conditions, it is also possible to form the geminal regioisomer as major product with the same catalyst. This regiodivergent outcome is explained by bi-versus monometallic reaction pathways.

Active Iron(II) Catalysts toward gem-Specific Dimerization of Terminal Alkynes

We report the syntheses and catalytic activity of a series of piano-stool iron complexes with the general formula [FeClCp (NHC)] (where NHC = N-heterocyclic carbene) toward the gem-specific dimerization of terminal alkynes. In comparison to our first-gene