144944-69-4

Upstream product

• 100-44-7 benzyl chloride 
• 111-85-3 n-chlorooctane 
• 5149-49-5 rac-3-(benzylsulfanyl)propane-1,2-diol 

Downstream Products

• 144944-73-0 (+/-)-1-O-(1,2-di-O-octyl-rac-3-thioglycerylphosphoryl)-myo-inositol 
• 144944-72-9 Thiophosphoric acid S-(2,3-bis-octyloxy-propyl) ester O-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentakis-benzyloxy-cyclohexyl) ester 

Relevant academic research and scientific papers

Synthesis of inositol phospholipids with thiophosphoester bonds

The synthesis of phosphatidylinositol (PI) analogues (±)1-O-(1-O-octadecanoyl-2-O-acetyl-rac-3-thioglycerylphosphoryl)-myo -inositol(7), (±)1-O-(1,2-di-O-octadecyl-rac-3-thioglycerylphosphoryl)-myo-inositol (14a), (±)1-O-(1,2-di-O-octyl-rac-3-thioglycerylphosphoryl)-myo-inositol(14b ) and (±)1-O-(1-O-octadecyl-2-O-methyl-rac-3-thioglycerylphosphoryl)-myo-in ositol(14c) designed to show a novel mode of PI-phospholipase C (PI-PLC) inhibition, is described.