5149-49-5

Basic information

• Product Name: 1,2-Propanediol, 3-[(phenylmethyl)thio]-
• CAS NO: 5149-49-5
• Molecular Formula: C10H14O2S
• Molecular Weight: 198.286
• Mol File: 5149-49-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,2-Propanediol, 3-[(phenylmethyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanediol, 3-[(phenylmethyl)thio]-(5149-49-5)
• EPA Substance Registry System: 1,2-Propanediol, 3-[(phenylmethyl)thio]-(5149-49-5)

Safety Data

• Hazardous Substances Data: 5149-49-5(Hazardous Substances Data)

Usage

Type of compound

Diol derivative with a thioether moiety

Usage

Intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals

Potential applications

Bio-based polymers and plasticizers

Environmental properties

Environmentally friendly

Researched properties

Antimicrobial and antibiotic properties

Value

Versatile and valuable chemical in various industries

Upstream product

• 93-14-1 guaifenesin 
• 100-53-8 phenylmethanethiol 
• 14007-09-1 2-(2-methoxyphenoxy)-1,3-propanediol 
• 96-27-5 rac-3-sulfanylpropane-1,2-diol 
• 100-44-7 benzyl chloride 
• 20256-77-3 2-(benzylsulfanylmethyl)oxirane 

Downstream Products

• 144944-50-3 rac-1-(benzylsulfanyl)-2,3-bis(octadecyloxy)propane 
• 1415795-32-2 benzyl(2,3-bis((9Z,12Z)-octadeca-9,12-dien-1-yloxy)propyl)sulfane 
• 1278996-66-9 1-(benzylthio)-3-(tert-butyldiphenylsilyloxy)propan-2-ol 
• 1278996-72-7 1-(benzylthio)-3-(tert-butyldiphenylsilyloxy)propan-2-biotinylamide 
• 1278996-71-6 1-(benzylthio)-3-(tert-butyldiphenylsilyloxy)propan-2-amine 
• 1278996-69-2 2-(1-(benzylthio)-3-(tert-butyldiphenylsilyloxy)propan-2-yl)isoindoline-1,3-dione 
• 676245-65-1 C₂₂H₃₈O₄S 
• 146490-99-5 (2-Methoxy-3-octadecyloxy-propylsulfanylmethyl)-benzene 
• 143994-75-6 2-Benzylsulfanylmethyl-1,4,7,10,13-pentaoxa-cyclopentadecane 
• 143994-73-4 2-Benzylsulfanylmethyl-1,4,7,10-tetraoxa-cyclododecane 
• 88738-56-1 3-Phenylmethanesulfinyl-propane-1,2-diol 
• 144944-69-4 (2,3-Bis-octyloxy-propylsulfanylmethyl)-benzene 

Relevant articles and documents

CLEAVABLE LIPIDS

Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent iransfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids.

Polyamine compounds and compositions containing them useful for the transfer of active substances into a cell

The application relates to polyamine telomer compounds comprising the group of the formula I wherein: A is H or an alkyl of 1 to 4 carbon atoms or an aryl of 5 to 7 carbon atoms, the degree of polymerization n ranges from 1 to 100, R1is selected, independently of one another in each [CH2-CA] nrepeat, from -H, -CH3, -C2H5and - (CH2)u-B, x and u are integers from 2 to 4, B being wherein: y is an integer from 2 to 4, z is an integer from 0 to 6, R3, R4, R5, R6and R7are selected, independently of one another, from H, alkyl or hydroxyalkyl of 1 to 4 carbon atoms.

Synthesis of inositol phospholipids with thiophosphoester bonds

The synthesis of phosphatidylinositol (PI) analogues (±)1-O-(1-O-octadecanoyl-2-O-acetyl-rac-3-thioglycerylphosphoryl)-myo -inositol(7), (±)1-O-(1,2-di-O-octadecyl-rac-3-thioglycerylphosphoryl)-myo-inositol (14a), (±)1-O-(1,2-di-O-octyl-rac-3-thioglycerylphosphoryl)-myo-inositol(14b ) and (±)1-O-(1-O-octadecyl-2-O-methyl-rac-3-thioglycerylphosphoryl)-myo-in ositol(14c) designed to show a novel mode of PI-phospholipase C (PI-PLC) inhibition, is described.