1449519-84-9Relevant articles and documents
Regioselective BF3·Et2O-catalyzed C-H functionalization of indoles and pyrrole with reaction of α-diazophosphonates
Cai, Yan,Li, Yuming,Zhang, Minxuan,Fu, Jiaxin,Miao, Zhiwei
, p. 69352 - 69356 (2016)
Facile regiospecific intermolecular C-H insertion reactions of α-diazophosphonates with indole or pyrrole derivatives catalyzed by trifluoroborane have been developed. The reaction protocol was effective for regioselective C-H insertion depending on the substitution pattern on the indole moiety and carbene migratory model. This represents the first straightforward access to N-unsubstituted β-(3-indol)-β-aminophosphonates and β-(2-pyrrol)-β-aminophosphonates containing quaternary carbon centers in moderate to good yields.
