1449846-89-2Relevant academic research and scientific papers
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells
Cavalluzzi, Maria Maddalena,Viale, Maurizio,Bruno, Claudio,Carocci, Alessia,Catalano, Alessia,Carrieri, Antonio,Franchini, Carlo,Lentini, Giovanni
, p. 4820 - 4823 (2013)
Lubeluzole, a neuroprotective anti-ischemic drug, and its enantiomer were prepared following a convenient procedure based on hydrolytic kinetic resolution. The ee values were >99% and 96%, respectively, as assessed by HPLC analysis. The chemosensitizing e
