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145011-61-6

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145011-61-6 Usage

General Description

2,5-Piperidinedicarboxylic acid, 1-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]-, 2,5-diMethyl ester, (2R,5S)-rel- is a chemical compound with the molecular formula C16H20N2O6. It is an ester of piperidinedicarboxylic acid and 1-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]. 2,5-Piperidinedicarboxylic acid, 1-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]-, 2,5-diMethyl ester, (2R,5S)-rel- has a 2R,5S stereochemistry and is composed of two piperidine rings and an isoindoline ring. It is commonly used in pharmaceutical research and drug development due to its potential pharmacological properties.

Check Digit Verification of cas no

The CAS Registry Mumber 145011-61-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,0,1 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 145011-61:
(8*1)+(7*4)+(6*5)+(5*0)+(4*1)+(3*1)+(2*6)+(1*1)=86
86 % 10 = 6
So 145011-61-6 is a valid CAS Registry Number.

145011-61-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name dimethyl (2R,5S)-1-[2-(1,3-dioxoisoindol-2-yl)ethyl]piperidine-2,5-dicarboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:145011-61-6 SDS

145011-61-6Relevant articles and documents

Process and intermediates for bis-aza-bicyclic anxiolytic agents

-

, (2008/06/13)

Optically pure intermediates of formula (1) wherein the substituent B is either cis or trans to the C9a -C1 bond and is selected from the group consisting of --CH2 OH, --CHO, --CH2 OSO2 R, --CH2 CN, --CH(OH)CH2 NO2, --CH=CH--NO2, (2) and (3), C is selected from the group consisting of --H, (4), (5), and a nitrogen protecting group which is removable by hydrogenation or acid treatment; and wherein R is (C1 -C8) alkyl, phenyl or alkyl substituted phenyl; X is N or CH; Y is O or S and Z is H or Cl; for the synthesis of octahydro-1H-pyrido(1,2-a)pyrazinyl ethyl carboxamide anxiolytic agents.

Process and intermediate for certain bis-aza-bicyclic anxiolytic agents

-

, (2008/06/13)

(C1 -C3)Alkyl-4,6,7,8,9,9a-hexahydro-2H,3H-pyrido[1,2-a]pyrazin-1-one-7-carboxylate esters, important precursors to certain bis-aza-bicyclic anxiolytics, can be prepared from di(C1 -C3)alkyl cis-piperidine-2,5-dicarboxylate starting material by a new process via a new class of intermediates, di(C1 -C3)alkyl cis-N-(2-(phthalimido)ethyl)piperidine-2,5-dicarboxylates. In the process, the starting material is reacted with either 2-(phthalimido)ethyl triflate or 2-(phthalimido)acetaldehyde to form the new intermediate, which can then be cyclized to the aforementioned precursor.

Process and intermediate for certain bis-aza-bicyclic anxiolytic agents

-

, (2008/06/13)

(C1 -C3)Alkyl-4,6,7,8,9,9a-hexahydro-2H,3H-pyrido-[1,2-a]pyrazin-1-one-7-carboxylate esters, important precursors to certain bis-aza-bicyclic anxiolytics, can be prepared from di(C1 -C3)alkyl cis-piperidine-2,5-dicarboxylate starting material by a new process via a new class of intermediates, di(C1 -C3)alkyl cis-N-(2-(phthalimido)ethyl)piperidine-2,5-dicarboxylates. In the process, the starting material is reacted with either 2-(phthalimido)ethyl triflate or 2-(phthalimido)acetaldehyde to form the new intermediate, which can then be cyclized to the aforementioned precursor.

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