2207-52-5

Basic information

• Product Name: 2,5-Piperidinedicarboxylic acid, 2,5-diMethyl ester
• Synonyms: 2,5-Piperidinedicarboxylic acid, 2,5-diMethyl ester;diMethyl piperidine-2,5-dicarboxylate;2,5-Dimethyl piperidine-2,5-dicarboxylate
• CAS NO: 2207-52-5
• Molecular Formula: C9H15NO4
• Molecular Weight: 201.2197
• Mol File: 2207-52-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 104-106 °C(Press: 0.4 Torr)
• Appearance: /
• Density: 1.132±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 7.10±0.10(Predicted)
• CAS DataBase Reference: 2,5-Piperidinedicarboxylic acid, 2,5-diMethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Piperidinedicarboxylic acid, 2,5-diMethyl ester(2207-52-5)
• EPA Substance Registry System: 2,5-Piperidinedicarboxylic acid, 2,5-diMethyl ester(2207-52-5)

Safety Data

• Hazardous Substances Data: 2207-52-5(Hazardous Substances Data)

Usage

Main Use

Building block in pharmaceuticals, agrochemicals, and organic compounds synthesis

Parent Compound

Piperidine, a heterocyclic amine

Derivative

It is derived from piperidine

Functional Groups

Two ester groups attached to the piperidine ring

Versatility

Serves as a versatile intermediate for synthesizing complex organic molecules

Reactivity

Exhibits significant reactivity in organic chemistry applications

Importance

Plays a crucial role in the field of organic chemistry

Upstream product

• 881-86-7 dimethyl 2,5-pyridine dicarboxylate 
• 67-56-1 methanol 
• 84229-41-4 trans-2,5-piperidinedicarboxylic acid 
• 499-81-0 3,5-Pyridinedicarboxylic acid 
• 84229-41-4 (+/-)-cis-2,5-piperidinedicarboxylic acid 

Downstream Products

• 145012-49-3 5-(methoxycarbonyl)piperidine-2-carboxylic acid 
• 105641-12-1 9-hydroxy-octahydro-quinolizin-3-carboxylic acid methyl ester 
• 145012-49-3 trans-5-(methoxycarbonyl)piperidine-2-carboxylic acid 
• 145012-49-3 cis-5-(methoxycarbonyl)piperidine-2-carboxylic acid 
• 144660-61-7 dimethyl trans-1-(2-(phthalimido)ethyl)piperidine-2,5-dicarboxylate 
• 145011-61-6 (2R,5R)-1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-piperidine-2,5-dicarboxylic acid dimethyl ester 

Relevant articles and documents

Preparation of differentiated diamides of 4,5,6,7-tetrahydropyrazolo[1,5-a] pyridine-2,6- and -3,6-dicarboxylic acids suitable for parallel synthesis

1,3-Dipolar cycloaddition of a bicyclic sydnone to a propargylic acid amide affords 4,5,6,7-tetra-hydropyrazolo[1,5-a]pyridine-2,6- and -3,6-dicarboxylic acid monoamides which are further converted to corresponding differentiated diamides.

Synthesis of trans-7-Hydroxymethyl-2-(2-benzisoxazol-3-yl)octahydro-2H-pyridopyrazine

An efficient synthesis of trans-7-hydroxymethyl-2-(2-benzisoxazol-3-yl)octahydro-2H-pyridopyrazine 2 is presented which relies on the equilibration of cis-dimethyl piperidinedicarboxylate followed by alkylation with phthalimidoethyl triflate.

Synthesis of tabtoxinine δ lactam

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