1450806-67-3

Upstream product

• 1012367-41-7 tert-butyl-(R)-(1-(4-methoxybenzyloxy)pent-4-en-2-yloxy)dimethylsilane 
• 745058-24-6 (R)-2-(tert-butyldimethylsilanyloxy)-pent-4-enal 
• 745058-47-3 (R)-2-(tert-butyldimethylsilanyloxy)-pent-4-en-1-ol 
• 194342-84-2 (R)-1-[(4-methoxybenzyl)oxy]pent-4-en-2-ol 

Downstream Products

• 174623-90-6 (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid 
• 174623-94-0 (2S,3R)-(R)-1-(benzyloxy)-3-methyl-1-oxobutan-2-yl-3-{[(3R,4S)-4-{[(benzyloxy)carbonyl](methyl)amino}-3-(methoxymethoxy)-5-phenylpentanoyl]oxy}-2-methyldecanoate 
• 127041-77-4 ((1S,2R)-1-Benzyl-2-hydroxy-pent-4-enyl)-carbamic acid benzyl ester 
• 174623-89-3 ((1S,2R)-1-Benzyl-2-methoxymethoxy-pent-4-enyl)-methyl-carbamic acid benzyl ester 

Relevant academic research and scientific papers

A highly stereoselective formal synthesis of hapalosin

A flexible and highly diastereoselective formal synthesis of hapalosin, a cyclodepsipeptide isolated from the blue green alga Hapalosiphon welwitschii and having multidrug-resistance-reversing activity is described. The synthetic route involves the addition of organometallic reagent to N-tert- butanesulfinylimine, Jung nonaldol aldol reaction, and Yamaguchi esterification as key steps. Georg Thieme Verlag Stuttgart · New York.