14509-66-1

Basic information

• Product Name: 7,8-dihydroimidazo[1,5-f]pyrimidin-5(6H)-one
• Synonyms: 7,8-dihydroimidazo[1,5-f]pyrimidin-5(6H)-one;IMidazo[1,5-c]pyriMidin-5(6H)-one, 7,8-dihydro-;5,6,7,8-Tetrahydro-5-oxoimidazo[1,5-c]pyrimidine;5,6,7,8-Tetrahydroimidazo[1,5-c]pyrimidin-5-one;7,8-Dihydroimidazo[1,5-c]pyrimidin-5(6H);7,8-Dihydro-6H-imidazo[1,5-c]pyrimidin-5-one
• CAS NO: 14509-66-1
• Molecular Formula: C₆H₇N₃O
• Molecular Weight: 137.13928
• Mol File: 14509-66-1.mol
• Article Data: 18

Chemical Properties

• Melting Point: 218-219℃
• Appearance: /
• Density: 1.53
• Refractive Index: 1.738
• Storage Temp.: 2-8°C
• PKA: 9.60±0.20(Predicted)
• CAS DataBase Reference: 7,8-dihydroimidazo[1,5-f]pyrimidin-5(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7,8-dihydroimidazo[1,5-f]pyrimidin-5(6H)-one(14509-66-1)
• EPA Substance Registry System: 7,8-dihydroimidazo[1,5-f]pyrimidin-5(6H)-one(14509-66-1)

Safety Data

• Hazardous Substances Data: 14509-66-1(Hazardous Substances Data)

Usage

General Description

7,8-dihydroimidazo[1,5-f]pyrimidin-5(6H)-one is a complex chemical compound that belongs to the heterocyclic organic compounds, specifically the class of imidazopyrimidines. These are compounds containing an imidazopyrimidine moiety, which is a pyrimidine fused to an imidazole. The structure is characterized by a 7,8-dihydroimidazo[1,5-f]pyrimidin-5(6H)-one framework. As with all chemicals, it has specific physical and chemical properties, including its molecular weight, melting point, boiling point, and solubility. Information regarding its specific uses or its chemical behavior may vary depending on its derivatives or its interaction with other compounds. More specific details about its use and properties are typically found in specialized chemical databases and research studies.

InChI:InChI=1/C6H7N3O/c10-6-8-2-1-5-3-7-4-9(5)6/h3-4H,1-2H2,(H,8,10)

Upstream product

• 13464-19-2 phenyl chlorothioformate 
• 51-45-6 histamine 
• 288-32-4 1H-imidazole 
• 6481-48-7 N₁-Methylhistamine dihydrochloride 
• 530-62-1 1,1'-carbonyldiimidazole 
• 5070-13-3 bis-(p-nitrophenyl) carbonate 
• 56-92-8 histamine dichloride 
• 51-45-6 histamine 

Downstream Products

• 479408-49-6 2-(1-ethyl-1H-imidazol-4-yl)-ethylamine 
• 479408-51-0 2-(1-isopropylimidazol-4-yl)ethanamine 
• 921203-29-4 2-methyl-5-oxo-5,6,7,8-tetrahydroimidazo[1,5-c]pyrimidin-2-ium 4-methylbenzenesulfonate 
• 64403-25-4 3-methyl-3,4,6,7-tetrahydro-5H-imidazo<4,5-c>pyridine 
• 501-75-7 N₁-methylhistamine 
• 351891-06-0 [2-(2-adamantan-1-yl-3-benzyl-3H-imidazol-4-yl)-ethyl]-carbamic acid methyl ester 
• 351891-24-2 N-carbomethoxy-2-cyclohexyl-3-benzylhistamine 
• 351891-28-6 [2-(3-benzyl-2-tert-butyl-3H-imidazol-4-yl)-ethyl]-carbamic acid methyl ester 
• 351891-27-5 [2-(3-benzyl-2-isopropyl-3H-imidazol-4-yl)-ethyl]-carbamic acid methyl ester 
• 351890-97-6 1-phenacyl-N-α-carbomethoxyhistamine 
• 351891-13-9 [2-(3-benzyl-3H-imidazol-4-yl)-ethyl]-carbamic acid methyl ester 
• 51720-37-7 2-methyl-5-oxo-5,6,7,8-tetrahydroimidazo<1,5-c>pyrimidinium iodide 

Relevant articles and documents

A Heteroditopic Hexa-imidazole 'Encapsulating' Podand and a Facially Differentiated Hexadentate Ligand

Syntheses of the facially differentiated tris-imidazole triamine (10) and of the novel 'hetero'-ditopic hexa-imidazole ligand (11), from histamine (3), are described.

2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924

A series of IGF-1R inhibitors is disclosed, wherein the (m-chlorophenyl)ethanol side chain of BMS-536924 (1) is replaced with a series of 2-(1H-imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chains. Some analogs show improved IGF-1R poten

FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE

The invention relates to compounds of formula (I) for the regulation of phosphoinositides 3-kinases activity and related diseases.