64403-25-4

Basic information

• Product Name: 4,5,6,7-tetrahydro-3-methyl-3H-Imidazo[4,5-c]pyridine
• Synonyms: 4,5,6,7-tetrahydro-3-methyl-3H-Imidazo[4,5-c]pyridine
• CAS NO: 64403-25-4
• Molecular Formula: C7H11N3
• Molecular Weight: 137.18234
• EINECS: -0
• Mol File: 64403-25-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,5,6,7-tetrahydro-3-methyl-3H-Imidazo[4,5-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5,6,7-tetrahydro-3-methyl-3H-Imidazo[4,5-c]pyridine(64403-25-4)
• EPA Substance Registry System: 4,5,6,7-tetrahydro-3-methyl-3H-Imidazo[4,5-c]pyridine(64403-25-4)

Safety Data

• Hazardous Substances Data: 64403-25-4(Hazardous Substances Data)

Upstream product

• 1421503-52-7 6,7-dihydro-4H-imidazo[4,5-c]pyridine-1,5-dicarboxylic acid di-tert-butyl ester 
• 6882-74-2 4,5,6,7-tetrahydro-1H-imidazo<4,5-c>pyridine 
• 1202800-68-7 1,4,6,7-tetrahydro-imidazo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester 
• 74-88-4 methyl iodide 
• 1026689-58-6 benzyl 3,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-5-carboxylate 
• 62002-31-7 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine dihydrochloride 
• 51720-37-7 2-methyl-5-oxo-5,6,7,8-tetrahydroimidazo<1,5-c>pyrimidinium iodide 
• 6882-74-2 4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine 
• 14509-66-1 5,6,7,8-tetrahydro-5-oxoimidazo[1,5-c]pyrimidine 
• 51-45-6 histamine 
• 74-83-9 methyl bromide 
• 501-75-7 N₁-methylhistamine 
• 504-63-2 trimethyleneglycol 

Relevant articles and documents

PRMT5 INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof:wherein Y1 is of formula (?) or formula (y):Ring Y is a 5- to 6-membered heteroaryl ring; and V4, V5, Rx, x, y, and n are as defined herein. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

DERIVATIVES OF N-[(1H-PYRAZOL-1-YL)ARYL]-1H-INDOLE OR 1H-INDAZOLE-3-CARBOXAMIDE, PREPARATION THEREOF AND APPLICATIONS THEREOF IN THERAPEUTICS

The present invention relates to compounds corresponding to formula (I): in which: A represents a divalent aromatic radical; X represents a —CH— group or a nitrogen atom; R1 represents a (C1-C4)alkyl or a (C1-C4)alkoxy; R2 represents a group Alk; R3 represents a hydroxyl or a group —NR7R8; R4 represents a hydrogen atom, a halogen atom, a cyano, a phenyl, a group Alk, a group OAlk or a group —NR9R10; R5 represents a hydrogen atom, a halogen atom or a group Alk; R6 represents a hydrogen atom, a halogen atom, a cyano, a group —COOAlk or a —CONH2 group.