1451004-46-8Relevant academic research and scientific papers
Pyridinium 1,4-zwitterionic thiolates as a useful class of sulfur-containing synthons: application to the synthesis of 2,5-dihydro-1,4,5-thiadiazepines
Cheng, Bin,Li, Yuntong,Wang, Taimin,Zhang, Xinping,Li, Hui,Li, Yun,Zhai, Hongbin
, p. 14606 - 14608 (2019)
A novel [4+3] cascade cyclization reaction of pyridinium 1,4-zwitterionic thiolates with azoalkenes derived from α-halo hydrazones in situ has been developed. This reaction was found to allow expedient access to an array of 2,5-dihydro-1,4,5-thiadiazepine
Silver(I)- and Base-Mediated formal [4+3] Cycloaddition of in Situ generated 1,2-Diaza-1,3-dienes with C,N-Cyclic Azomethine Imines: An Efficient Protocol for the Synthesis of Tetrazepine Derivatives
Li, Zefei,Li, Shuaikang,Kan, Tianjiao,Wang, Xinyue,Xin, Xin,Hou, Yunlei,Gong, Ping
supporting information, p. 2626 - 2631 (2020/06/04)
A silver(I)- and base-mediated formal [4+3] cycloaddition reaction of in situ generated 1,2-diaza-1,3-dienes with in situ formed C,N-cyclic azomethine imines has been developed. This protocol provided an efficient method for the synthesis of biologically important 1,2,4,5-tetrazepine derivatives with a wild substrate scope and excellent functional group tolerance in moderate to excellent yields. (Figure presented.).
Synthesis of Bicyclo[4.1.0]tetrahydropyridazines by a Sequential [4 + 2] and [1 + 2] Annulation Reaction of Azoalkenes and Crotonate-Derived Sulfur Ylides
Yin, Wenhao,Fang, Ling,Wang, Zhiyong,Gao, Fang,Li, Zhefeng,Wang, Zhiyong
supporting information, p. 7361 - 7364 (2019/10/02)
The base-induced unprecedented tandem [4 + 2] and [1 + 2] annulation reaction of in situ formed 1,2-diaza-1,3-dienes and crotonate-derived sulfur ylides is reported. This protocol provides a novel and practical method for the synthesis of cyclopropane-fused tetrahydropyridazines with a quaternary carbon center in synthetically useful yield. In this tandem reaction, three new bonds were formed in one pot, and the crotonate-derived sulfur ylide serves as a C3 synthon.
Cycloaddition of in situ generated azoalkenes with C,N-cyclic azomethine imines: Efficient synthesis of tetrazepine derivatives
Hu, Xiao-Qiang,Chen, Jia-Rong,Gao, Shuang,Feng, Bin,Lu, Liang-Qiu,Xiao, Wen-Jing
supporting information, p. 7905 - 7907 (2013/09/02)
An unprecedented [4+3] cycloaddition of in situ generated azoalkenes with C,N-cyclic azomethine imines has been developed without the use of any catalyst, providing an efficient and mild approach to synthesise highly functionalized 1,2,4,5-tetrazepine der
